Background In hypertension, sodium sensitivity (SS) of blood pressure is associated with
renal hemodynamic abnormalities related to increased activity of the renal renin …

Many patients with essential hypertension respond to a high dietary sodium intake with a
rise in blood pressure. Experimental evidence suggests that the renal hemodynamic …

Objectives Several mechanisms have been proposed for salt-sensitive hypertension, with
most focusing on impaired renal sodium handling. We tested the hypothesis that …

Objective An increased sensitivity to angiotensin II (Ang II) has been observed in patients
with established hypertension. In the current study we tested whether young normotensive …

Objective: Urinary excretion of angiotensinogen [urine angiotensinogen (UAGT)] has been
proposed as a biomarker of intrarenal renin–angiotensin system activity. We investigated the …

Low-renin essential hypertension (LREH) describes a widely recognized classification
validated by clinical features, including salt-sensitive blood pressure and diuretic …

The regulation of both angiotensin receptors and bradykinin receptors during sodium intake
is poorly understood. We hypothesized that an altered balance between renal angiotensin …

The inability of mineralocorticoid receptor (MR) blockade to reduce hypertension associated
with high angiotensin (Ang) II suggests direct actions of Ang II to regulate tubular sodium …

To examine the role of adrenergic activity on the reduction in nephron filtration rate during
chronic sodium depletion in rats, we have measured all the determinants of glomerular …

We recently showed that cardiovascular morbidity was higher in sodium sensitive type of
essential hypertension than in the non-sodium sensitive type. It was examined whether …