Eosinophils are implicated in the pathophysiology of respiratory virus infection, most
typically in negative roles, such as promoting wheezing and bronchoconstriction in …

In this review, we consider the role played by eosinophilic leukocytes in the pathogenesis
and pathophysiology of respiratory virus infection. The vast majority of the available …

Eosinophils are recruited to the lung in response to infection with pneumovirus pathogens
and have been associated with both the pathophysiologic sequelae of infection and, more …

Eosinophils have been mainly associated with parasitic infection and pathologies such as
asthma. Some patients with asthma present a high number of eosinophils in their airways …

Eosinophils are recruited to the airways as a prominent feature of the asthmatic inflammatory
response where they are broadly perceived as promoting pathophysiology. Respiratory …

Human eosinophils secrete two distinct ribonucleases that have antiviral activity against
pathogens of the family Paramyxoviridae. To examine the role of eosinophils and their …

Background Activated eosinophils cause major pathology in stable and exacerbating
asthma; however, they can also display protective properties like an extracellular antiviral …

Enhanced disease is the term used to describe the aberrant Th2-skewed responses to
naturally acquired human respiratory syncytial virus (hRSV) infection observed in individuals …

BACKGROUND: The most frequent trigger of asthma exacerbation is infection with common
airway viruses; however, the precise mechanism regulating such severe reactions is not …

Several lines of investigation have indicated a role for eosinophilic leukocytes in limiting
virus infectivity and promoting virion clearance. We have established a respiratory virus …