New perspectives on pheochromocytoma and paraganglioma: toward a molecular classification

J Crona, D Taïeb, K Pacak - Endocrine reviews, 2017 - academic.oup.com
A molecular biology–based taxonomy has been proposed for pheochromocytoma and
paraganglioma (PPGL). Data from the Cancer Genome Atlas revealed clinically relevant …

Pheochromocytoma: a genetic and diagnostic update

LB Mercado-Asis, KI Wolf, I Jochmanova, D Taïeb - Endocrine practice, 2018 - Elsevier
ABSTRACT Objective: Pheochromocytomas and paragangliomas (PPGLs) are
neuroendocrine tumors derived from adrenal or extra-adrenal locations, respectively. Upon …

Precision medicine in pheochromocytoma and paraganglioma: current and future concepts

P Björklund, K Pacak, J Crona - Journal of internal medicine, 2016 - Wiley Online Library
Pheochromocytoma and paraganglioma (PPGL) are rare diseases but are also amongst the
most characterized tumour types. Hence, patients with PPGL have greatly benefited from …

[HTML][HTML] Update of pheochromocytoma syndromes: genetics, biochemical evaluation, and imaging

R Alrezk, A Suarez, I Tena, K Pacak - Frontiers in Endocrinology, 2018 - frontiersin.org
Pheochromocytomas and paragangliomas (PCCs/PGLs) are rare commonly benign
neuroendocrine tumors that share pathology features and clinical behavior in many cases …

[HTML][HTML] Pheochromocytoma/paraganglioma: recent updates in genetics, biochemistry, immunohistochemistry, metabolomics, imaging and therapeutic options

K Antonio, MMN Valdez, L Mercado-Asis, D Taïeb… - Gland …, 2020 - ncbi.nlm.nih.gov
Pheochromocytomas and paragangliomas (PPGLs), rare chromaffin/neural crest cell tumors,
are commonly benign in their clinical presentation. However, there are a number of cases …

[HTML][HTML] Genetic bases of pheochromocytoma and paraganglioma

A Cascón, B Calsina, M Monteagudo… - Journal of …, 2023 - jme.bioscientifica.com
The genetics of pheochromocytoma and paraganglioma (PPGL) has become increasingly
complex over the last two decades. The list of genes involved in the development of these …

[HTML][HTML] Current management of pheochromocytoma/paraganglioma: a guide for the practicing clinician in the era of precision medicine

S Nölting, M Ullrich, J Pietzsch, CG Ziegler… - Cancers, 2019 - mdpi.com
Pheochromocytomas and paragangliomas (PCC/PGLs) are rare, mostly catecholamine-
producing neuroendocrine tumors of the adrenal gland (PCCs) or the extra-adrenal …

Pheochromocytoma and paraganglioma: diagnosis, genetics, management, and treatment

VL Martucci, K Pacak - Current problems in cancer, 2014 - Elsevier
Pheochromocytomas (PHEOs) are rare neuroendocrine tumors that arise from the
chromaffin cells of the adrenal glands. Paragangliomas (PGLs), the extra-adrenal …

Pheochromocytoma: a changing perspective and current concepts

A Kiriakopoulos, P Giannakis… - … in endocrinology and …, 2023 - journals.sagepub.com
This article aims to review current concepts in diagnosing and managing
pheochromocytoma and paraganglioma (PPGL). Personalized genetic testing is vital, as 40 …

Pheochromocytoma and paraganglioma pathogenesis: learning from genetic heterogeneity

PLM Dahia - Nature Reviews Cancer, 2014 - nature.com
The neuroendocrine tumours pheochromocytomas and paragangliomas carry the highest
degree of heritability in human neoplasms, enabling genetic alterations to be traced to …