[HTML][HTML] Pathological roles of MAPK signaling pathways in human diseases
EK Kim, EJ Choi - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2010 - Elsevier
The mammalian family of mitogen-activated protein kinases (MAPKs) includes extracellular
signal-regulated kinase (ERK), p38, and c-Jun NH2-terminal kinase (JNK), with each MAPK …
signal-regulated kinase (ERK), p38, and c-Jun NH2-terminal kinase (JNK), with each MAPK …
The complexity of mitogen-activated protein kinases (MAPKs) made simple
M Krishna, H Narang - Cellular and Molecular Life Sciences, 2008 - Springer
The mitogen-activated protein kinase (MAPK) pathways are known to be involved in various
processes of growth, differentiation and cell death. In spite of their ubiquitous presence and …
processes of growth, differentiation and cell death. In spite of their ubiquitous presence and …
Compromised MAPK signaling in human diseases: an update
EK Kim, EJ Choi - Archives of toxicology, 2015 - Springer
The mitogen-activated protein kinases (MAPKs) in mammals include c-Jun NH 2-terminal
kinase (JNK), p38 MAPK, and extracellular signal-regulated kinase (ERK). These enzymes …
kinase (JNK), p38 MAPK, and extracellular signal-regulated kinase (ERK). These enzymes …
Differential regulation and properties of MAPKs
M Raman, W Chen, MH Cobb - Oncogene, 2007 - nature.com
Mitogen-activated protein kinases (MAPKs) regulate diverse cellular programs including
embryogenesis, proliferation, differentiation and apoptosis based on cues derived from the …
embryogenesis, proliferation, differentiation and apoptosis based on cues derived from the …
MAPKs: new targets for neurodegeneration
SJ Harper, N Wilkie - Expert opinion on therapeutic targets, 2003 - Taylor & Francis
Neurodegenerative diseases remain a huge unmet pharmaceutical need. For some
diseases such as Parkinson's disease, there are currently only palliative therapies, and for …
diseases such as Parkinson's disease, there are currently only palliative therapies, and for …
Phosphatase‐mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
MR Junttila, SP Li, J Westermarck - The FASEB Journal, 2008 - Wiley Online Library
Mitogen‐activated protein kinase (MAPK) pathways constitute a large modular network that
regulates a variety of physiological processes, such as cell growth, differentiation, and …
regulates a variety of physiological processes, such as cell growth, differentiation, and …
Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway
P Gerwins, LB Jonathan, GL Johnson - Journal of Biological Chemistry, 1997 - ASBMB
Mitogen-activated protein kinases (MAPKs) are components of sequential kinase cascades
that are activated in response to a variety of extracellular signals. Members of the MAPK …
that are activated in response to a variety of extracellular signals. Members of the MAPK …
[HTML][HTML] Atypical mitogen-activated protein kinases: structure, regulation and functions
P Coulombe, S Meloche - Biochimica et Biophysica Acta (BBA)-Molecular …, 2007 - Elsevier
Mitogen-activated protein (MAP) kinases are a family of serine/threonine kinases that play a
central role in transducing extracellular cues into a variety of intracellular responses ranging …
central role in transducing extracellular cues into a variety of intracellular responses ranging …
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
GL Johnson, R Lapadat - Science, 2002 - science.org
Multicellular organisms have three well-characterized subfamilies of mitogen-activated
protein kinases (MAPKs) that control a vast array of physiological processes. These …
protein kinases (MAPKs) that control a vast array of physiological processes. These …
The role of mitogen-activated protein kinase-activated protein kinases (MAPKAPKs) in inflammation
U Moens, S Kostenko, B Sveinbjørnsson - Genes, 2013 - mdpi.com
Mitogen-activated protein kinase (MAPK) pathways are implicated in several cellular
processes including proliferation, differentiation, apoptosis, cell survival, cell motility …
processes including proliferation, differentiation, apoptosis, cell survival, cell motility …