Transforming growth factor-β receptors and Smads: regulatory complexity and functional versatility
EH Budi, D Duan, R Derynck - Trends in cell biology, 2017 - cell.com
Transforming growth factor (TGF)-β family proteins control cell physiology, proliferation, and
growth, and direct cell differentiation, thus playing key roles in normal development and …
growth, and direct cell differentiation, thus playing key roles in normal development and …
Negative regulation of TGF-β receptor/Smad signal transduction
S Itoh, P ten Dijke - Current opinion in cell biology, 2007 - Elsevier
Members of the transforming growth factor-β (TGF-β) family are highly conserved
multifunctional cell–cell signaling proteins that are of key importance for controlling …
multifunctional cell–cell signaling proteins that are of key importance for controlling …
New insights into TGF-β–Smad signalling
P ten Dijke, CS Hill - Trends in biochemical sciences, 2004 - cell.com
Transforming growth factor β (TGF-β) initiates its diverse cellular responses by binding to
and activating specific cell surface receptors that have intrinsic serine/threonine kinase …
and activating specific cell surface receptors that have intrinsic serine/threonine kinase …
TGF-β signaling from receptors to Smads
A Hata, YG Chen - Cold Spring Harbor perspectives in …, 2016 - cshperspectives.cshlp.org
Transforming growth factor β (TGF-β) and related growth factors are secreted pleiotropic
factors that play critical roles in embryogenesis and adult tissue homeostasis by regulating …
factors that play critical roles in embryogenesis and adult tissue homeostasis by regulating …
[HTML][HTML] Post-translational regulation of TGF-β receptor and Smad signaling
P Xu, J Liu, R Derynck - FEBS letters, 2012 - Elsevier
TGF-β family signaling through Smads is conceptually a simple and linear signaling
pathway, driven by sequential phosphorylation, with type II receptors activating type I …
pathway, driven by sequential phosphorylation, with type II receptors activating type I …
Specificity, diversity, and regulation in TGF‐β superfamily signaling
E Piek, CH HELDIN, PTEN DIJKE - The FASEB Journal, 1999 - Wiley Online Library
Transforming growth factor‐β (TGF‐β) superfamily members are multifunctional cell‐cell
signaling proteins that play pivotal roles in tissue homeostasis and development of …
signaling proteins that play pivotal roles in tissue homeostasis and development of …
New regulatory mechanisms of TGF-β receptor function
JS Kang, C Liu, R Derynck - Trends in cell biology, 2009 - cell.com
Transforming growth factor-β (TGF-β) regulates cell proliferation, differentiation and
apoptosis, and TGF-β-related proteins have key roles in development, tissue homeostasis …
apoptosis, and TGF-β-related proteins have key roles in development, tissue homeostasis …
Posttranslational regulation of Smads
Transforming growth factor β (TGF-β) family signaling dictates highly complex programs of
gene expression responses, which are extensively regulated at multiple levels and vary …
gene expression responses, which are extensively regulated at multiple levels and vary …
Non-Smad signaling pathways of the TGF-β family
YE Zhang - Cold Spring Harbor perspectives in biology, 2017 - cshperspectives.cshlp.org
Transforming growth factor β (TGF-β) and structurally related factors use several intracellular
signaling pathways in addition to Smad signaling to regulate a wide array of cellular …
signaling pathways in addition to Smad signaling to regulate a wide array of cellular …
TGFβ–SMAD signal transduction: molecular specificity and functional flexibility
B Schmierer, CS Hill - Nature reviews Molecular cell biology, 2007 - nature.com
Ligands of the transforming growth factor-β (TGFβ) superfamily of growth factors initiate
signal transduction through a bewildering complexity of ligand–receptor interactions …
signal transduction through a bewildering complexity of ligand–receptor interactions …