Resistance exercise, but not endurance exercise, induces IKKβ phosphorylation in human skeletal muscle of training-accustomed individuals
AB Møller, MH Vendelbo, SK Rahbek… - … -European Journal of …, 2013 - Springer
The mammalian target of rapamycin complex 1 (mTORC1) is considered an important role in
the muscular adaptations to exercise. It has been proposed that exercise-induced signaling …
the muscular adaptations to exercise. It has been proposed that exercise-induced signaling …
Regulation of IκB kinase and NF-κB in contracting adult rat skeletal muscle
RC Ho, MF Hirshman, Y Li, D Cai… - … of Physiology-Cell …, 2005 - journals.physiology.org
Nuclear factor-κB (NF-κB) is a transcription factor with important roles in regulating innate
immune and inflammatory responses. NF-κB is activated through the phosphorylation of its …
immune and inflammatory responses. NF-κB is activated through the phosphorylation of its …
Signals mediating skeletal muscle remodeling by resistance exercise: PI3-kinase independent activation of mTORC1
For over 10 years, we have known that the activation of the mammalian target of rapamycin
complex 1 (mTORC1) has correlated with the increase in skeletal muscle size and strength …
complex 1 (mTORC1) has correlated with the increase in skeletal muscle size and strength …
The missing Akt in the mechanical regulation of skeletal muscle mTORC1 signalling and growth
BB Rasmussen - The Journal of Physiology, 2011 - ncbi.nlm.nih.gov
The mammalian target of rapamycin complex 1 (mTORC1) signalling pathway is a primary
regulator of skeletal muscle growth. Ten years ago it was reported that the overexpression of …
regulator of skeletal muscle growth. Ten years ago it was reported that the overexpression of …
Transient activation of mTORC1 signaling in skeletal muscle is independent of Akt1 regulation
M Miyazaki, N Moriya, T Takemasa - Physiological Reports, 2020 - Wiley Online Library
The regulation of cellular protein synthesis is a critical determinant of skeletal muscle growth
and hypertrophy in response to an increased workload such as resistance exercise. The …
and hypertrophy in response to an increased workload such as resistance exercise. The …
Repeated bouts of resistance exercise attenuate mitogen-activated protein-kinase signal responses in rat skeletal muscle
J Takegaki, K Sase, S Fujita - Biochemical and biophysical research …, 2019 - Elsevier
Resistance exercise training induces skeletal muscle hypertrophy, but repeated bouts
gradually attenuate this anabolic effect. Attenuation of mechanistic target of rapamycin …
gradually attenuate this anabolic effect. Attenuation of mechanistic target of rapamycin …
Resistance exercise induced mTORC1 signaling is not impaired by subsequent endurance exercise in human skeletal muscle
W Apró, L Wang, M Pontén… - American Journal of …, 2013 - journals.physiology.org
The current dogma is that the muscle adaptation to resistance exercise is blunted when
combined with endurance exercise. The suggested mechanism (based on rodent …
combined with endurance exercise. The suggested mechanism (based on rodent …
High-intensity muscle contraction-mediated increases in Akt1 and Akt2 phosphorylation do not contribute to mTORC1 activation and muscle protein synthesis
Y Maruyama, C Ikeda, K Wakabayashi… - Journal of Applied …, 2020 - journals.physiology.org
High-intensity muscle contraction (HiMC) is known to induce muscle protein synthesis, a
process in which mechanistic target of rapamycin (mTOR) is reported to play a critical role …
process in which mechanistic target of rapamycin (mTOR) is reported to play a critical role …
Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3‐kinase/Akt signalling
M Miyazaki, JJ McCarthy, MJ Fedele… - The Journal of …, 2011 - Wiley Online Library
Non‐technical summary Hypertrophy of skeletal muscle in response to resistance exercise
is associated with significantly elevated rates of protein synthesis. The protein kinase …
is associated with significantly elevated rates of protein synthesis. The protein kinase …
Resistance exercise increases intramuscular NF-κb signaling in untrained males
Abstract Purpose The NF-κB signaling pathway regulates multiple cellular processes
following exercise stress. This study aims to examine the effects of an acute lower-body …
following exercise stress. This study aims to examine the effects of an acute lower-body …