Differentiated mTOR but not AMPK signaling after strength vs endurance exercise in training‐accustomed individuals
The influence of adenosine mono phosphate (AMP)‐activated protein kinase (AMPK) vs Akt‐
mammalian target of rapamycin C 1 (mTORC1) protein signaling mechanisms on converting …
mammalian target of rapamycin C 1 (mTORC1) protein signaling mechanisms on converting …
Contraction‐regulated mTORC1 and protein synthesis: Influence of AMPK and glycogen
JR Knudsen, Z Li, KW Persson, J Li… - The Journal of …, 2020 - Wiley Online Library
Key points AMP‐activated protein kinase (AMPK)‐dependent Raptor Ser792
phosphorylation does not influence mechanistic target of rapamycin complex 1 (mTORC1) …
phosphorylation does not influence mechanistic target of rapamycin complex 1 (mTORC1) …
Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B-and growth factor-independent mechanism
TA Hornberger, R Stuppard, KE Conley… - Biochemical …, 2004 - portlandpress.com
In response to growth factors, mTOR (mammalian target of rapamycin) has been identified
as a central component of the signalling pathways that control the translational machinery …
as a central component of the signalling pathways that control the translational machinery …
Akt signalling through GSK‐3β, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy
B Léger, R Cartoni, M Praz, S Lamon… - The Journal of …, 2006 - Wiley Online Library
Skeletal muscle size is tightly regulated by the synergy between anabolic and catabolic
signalling pathways which, in humans, have not been well characterized. Akt has been …
signalling pathways which, in humans, have not been well characterized. Akt has been …
Normal hypertrophy accompanied by phosphoryation and activation of AMP‐activated protein kinase α1 following overload in LKB1 knockout mice
The activation of the AMP‐activated protein kinase (AMPK) and inhibition of the mammalian
target of rapamycin complex 1 (mTORC1) is hypothesized to underlie the fact that muscle …
target of rapamycin complex 1 (mTORC1) is hypothesized to underlie the fact that muscle …
Intramuscular anabolic signaling and endocrine response following resistance exercise: implications for muscle hypertrophy
Maintaining skeletal muscle mass and function is critical for disease prevention, mobility and
quality of life, and whole-body metabolism. Resistance exercise is known to be a major …
quality of life, and whole-body metabolism. Resistance exercise is known to be a major …
[HTML][HTML] ATP-induced increase in intracellular calcium levels and subsequent activation of mTOR as regulators of skeletal muscle hypertrophy
N Ito, UT Ruegg, S Takeda - International journal of molecular sciences, 2018 - mdpi.com
Intracellular signaling pathways, including the mammalian target of rapamycin (mTOR) and
the mitogen-activated protein kinase (MAPK) pathway, are activated by exercise, and …
the mitogen-activated protein kinase (MAPK) pathway, are activated by exercise, and …
Effects of age and sedentary lifestyle on skeletal muscle NF-κB signaling in men
Background. Nuclear factor kappa B (NF-κB) is a critical signaling molecule of disuse-
induced skeletal muscle atrophy. However, few studies have carefully investigated whether …
induced skeletal muscle atrophy. However, few studies have carefully investigated whether …
Contraction mode itself does not determine the level of mTORC1 activity in rat skeletal muscle
S Ato, Y Makanae, K Kido, S Fujita - Physiological reports, 2016 - Wiley Online Library
Resistance training with eccentric contraction has been shown to augment muscle
hypertrophy more than other contraction modes do (ie, concentric and isometric contraction) …
hypertrophy more than other contraction modes do (ie, concentric and isometric contraction) …
Resistance exercise-induced S6K1 kinase activity is not inhibited in human skeletal muscle despite prior activation of AMPK by high-intensity interval cycling
Combining endurance and strength training in the same session has been reported to
reduce the anabolic response to the latter form of exercise. The underlying mechanism …
reduce the anabolic response to the latter form of exercise. The underlying mechanism …