RNA-centric approaches to profile the RNA–protein interaction landscape on selected RNAs

AP Gerber - Non-coding RNA, 2021 - mdpi.com
RNA–protein interactions frame post-transcriptional regulatory networks and modulate
transcription and epigenetics. While the technological advances in RNA sequencing have …

RStrucFam: a web server to associate structure and cognate RNA for RNA-binding proteins from sequence information

P Ghosh, OK Mathew, R Sowdhamini - BMC bioinformatics, 2016 - Springer
Background RNA-binding proteins (RBPs) interact with their cognate RNA (s) to form large
biomolecular assemblies. They are versatile in their functionality and are involved in a …

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

B Lang, JS Yang, M Garriga-Canut… - Nucleic Acids …, 2021 - academic.oup.com
RNA-binding proteins (RBPs) are crucial factors of post-transcriptional gene regulation and
their modes of action are intensely investigated. At the center of attention are RNA motifs that …

RNA–protein interactions in vivo: global gets specific

ML Änkö, KM Neugebauer - Trends in biochemical sciences, 2012 - cell.com
RNA-binding proteins (RBPs) impact every process in the cell; they act as splicing and
polyadenylation factors, transport and localization factors, stabilizers and destabilizers …

Handshakes and fights: the regulatory interplay of RNA-binding proteins

E Dassi - Frontiers in molecular biosciences, 2017 - frontiersin.org
What drives the flow of signals controlling the outcome of post-transcriptional regulation of
gene expression? This regulatory layer, presiding to processes ranging from splicing to …

[HTML][HTML] HydRA: Deep-learning models for predicting RNA-binding capacity from protein interaction association context and protein sequence

W Jin, KW Brannan, K Kapeli, SS Park, HQ Tan… - Molecular Cell, 2023 - cell.com
RNA-binding proteins (RBPs) control RNA metabolism to orchestrate gene expression and,
when dysfunctional, underlie human diseases. Proteome-wide discovery efforts predict …

An analysis of conformational changes upon RNA-protein binding

K Sankar, RR Walia, CM Mann, RL Jernigan… - Proceedings of the 5th …, 2014 - dl.acm.org
RNA-binding proteins (RBPs) have myriad functions in transcription, translation, and post-
transcriptional gene regulation, with central roles in normal development as well as in both …

Integrating thermodynamic and sequence contexts improves protein-RNA binding prediction

Y Su, Y Luo, X Zhao, Y Liu, J Peng - PLoS computational biology, 2019 - journals.plos.org
Predicting RNA-binding protein (RBP) specificity is important for understanding gene
expression regulation and RNA-mediated enzymatic processes. It is widely believed that …

BRIO: a web server for RNA sequence and structure motif scan

A Guarracino, G Pepe, F Ballesio… - Nucleic acids …, 2021 - academic.oup.com
The interaction between RNA and RNA-binding proteins (RBPs) has a key role in the
regulation of gene expression, in RNA stability, and in many other biological processes …

Deciphering the role of RNA-binding proteins in the post-transcriptional control of gene expression

S Kishore, S Luber, M Zavolan - Briefings in functional genomics, 2010 - academic.oup.com
Eukaryotic cells express a large variety of ribonucleic acid-(RNA)-binding proteins (RBPs)
with diverse affinity and specificity towards target RNAs that play a crucial role in almost …