Lung inflammation caused by inhaled toxicants: a review

J Wong, BE Magun, LJ Wood - International journal of chronic …, 2016 - Taylor & Francis
Exposure of the lungs to airborne toxicants from different sources in the environment may
lead to acute and chronic pulmonary or even systemic inflammation. Cigarette smoke is the …

PM10-exposed macrophages stimulate a proinflammatory response in lung epithelial cells via TNF-α

LA Jimenez, EM Drost, PS Gilmour… - … of Physiology-Lung …, 2002 - journals.physiology.org
There is now considerable evidence for an association between the levels of particulate air
pollution [particulate matter< 10 μm in aerodynamic diameter (PM10)] and various adverse …

Effects of airway exposure to nanoparticles on lung inflammation induced by bacterial endotoxin in mice

K Inoue, H Takano, R Yanagisawa… - Environmental …, 2006 - ehp.niehs.nih.gov
Background Although adverse health effects of particulate matter with a diameter of< 100 nm
(nanoparticles) have been proposed, molecular and/or experimental evidence for their …

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

N Li, T Xia, AE Nel - Free radical biology and medicine, 2008 - Elsevier
Ambient particulate matter (PM) is an environmental factor that has been associated with
increased respiratory morbidity and mortality. The major effect of ambient PM on the …

The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress

AE Nel, D Diaz-Sanchez, N Li - Current opinion in pulmonary …, 2001 - journals.lww.com
We review the literature indicating that the adverse health effects of ambient particulate
matter involve the generation of oxidative stress and inflammation, as well as …

Aggravating impact of nanoparticles on immune‐mediated pulmonary inflammation

KI Inoue, H Takano - The Scientific World Journal, 2011 - Wiley Online Library
Although the adverse health effects of nanoparticles have been proposed and are being
clarified, their aggravating effects on pre‐existing pathological conditions have not been fully …

Effects of inhaled nanoparticles on acute lung injury induced by lipopolysaccharide in mice

K Inoue, H Takano, R Yanagisawa, S Hirano… - Toxicology, 2007 - Elsevier
We have previously shown that intratracheal instillation of carbon nanoparticles exacerbates
lung inflammation related to bacterial endotoxin (lipopolysaccharide, LPS) and subsequent …

Reactive oxygen species in pulmonary inflammation by ambient particulates

F Tao, B Gonzalez-Flecha, L Kobzik - Free Radical Biology and Medicine, 2003 - Elsevier
Exposure to ambient air pollution particles (PM) has been associated with increased
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …

Physicochemical characteristics of nanomaterials that affect pulmonary inflammation

HM Braakhuis, MVDZ Park, I Gosens… - Particle and fibre …, 2014 - Springer
The increasing manufacture and use of products based on nanotechnology raises concerns
for both workers and consumers. Various studies report induction of pulmonary inflammation …

Airborne particles evoke an inflammatory response in human airway epithelium. Activation of transcription factors

A Baeza-Squiban, V Bonvallot, S Boland… - Cell biology and …, 1999 - Springer
PM10, the commonly used indicator of respirable environmental suspended particulate
matter with a mean aerodynamic diameter of less than 10 μm, is composed of organic or …