MicroRNA-128 knockout inhibits the development of Alzheimer's disease by targeting PPARγ in mouse models

Y Liu, Y Zhang, P Liu, H Bai, X Li, J Xiao, Q Yuan… - European journal of …, 2019 - Elsevier
Alzheimer's disease (AD) is a great threat for the health and life of elderly people. MicroRNA-
128 (miR-128) has been reported to be abnormally expressed in the brain of AD patients …

[PDF][PDF] Inhibition of miR-128 abates Aβ-mediated cytotoxicity by targeting PPAR-γ via NF-κB inactivation in primary mouse cortical neurons and Neuro2a cells

L Geng, T Zhang, W Liu, Y Chen - Yonsei medical journal, 2018 - synapse.koreamed.org
Purpose Alzheimer's disease (AD) is the sixth most common cause of death in the United
States. MicroRNAs have been identified as vital players in neurodegenerative diseases …

A new discovery of MicroRNA-455-3p in Alzheimer's disease

S Kumar, PH Reddy - Journal of Alzheimer's Disease, 2019 - content.iospress.com
MicroRNA-455-3p (miR-455-3p) is identify as a member of broadly conserved miRNA family
expressed in most of the phylum and species. In humans, miR-455 is present on the human …

MiR-335-5p inhibits β-amyloid (Aβ) accumulation to attenuate cognitive deficits through targeting c-jun-N-terminal kinase 3 in Alzheimer's disease

D Wang, Z Fei, S Luo, H Wang - Current neurovascular …, 2020 - ingentaconnect.com
Objective: Alzheimer's disease (AD), also known as senile dementia, is a common
neurodegenerative disease characterized by progressive cognitive impairment and …

miR-30a-5p induces Aβ production via inhibiting the nonamyloidogenic pathway in Alzheimer's disease

T Sun, K Zhao, M Liu, Z Cai, L Zeng, J Zhang… - Pharmacological …, 2022 - Elsevier
Alzheimer's disease (AD) pathogenesis is known to involve a dysregulation of microRNA
expression, and these intricate transcriptional cascades between multiple pathological …

MicroRNA-140 silencing represses the incidence of Alzheimer's disease

C Liang, Y Mu, H Tian, D Wang, S Zhang, H Wang… - Neuroscience …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative condition leading to severe disability from
progressive impairments in cognitive functions including memory and learning. Non-coding …

MicroRNA-135b has a neuroprotective role via targeting of β-site APP-cleaving enzyme 1

Y Zhang, H Xing, S Guo, Z Zheng… - Experimental and …, 2016 - spandidos-publications.com
MicroRNAs (miRs) are a class of endogenous small non-coding RNAs that have been
revealed to negatively mediate the expression of their target genes at the post …

The role of microRNA-34 family in Alzheimer's disease: A potential molecular link between neurodegeneration and metabolic disorders

M Bazrgar, P Khodabakhsh, M Prudencio… - Pharmacological …, 2021 - Elsevier
Growing evidence indicates that overexpression of the microRNA-34 (miR-34) family in the
brain may play a crucial role in Alzheimer's disease (AD) pathogenesis by targeting and …

RETRACTED: MicroRNA-125b promotes neurons cell apoptosis and Tau phosphorylation in Alzheimer's disease

X Ma, L Liu, J Meng - 2017 - Elsevier
Numerous studies have reported that miR-125b is elevated in different brain regions of AD
patients compared to healthy individuals (Lukiw and Alexandrov, 2012; Richardson et al …

Targeting MicroRNA-485-3p blocks Alzheimer's disease progression

HS Koh, SJ Lee, HJ Lee, JW Min, T Iwatsubo… - International journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is a form of dementia characterized by progressive memory
decline and cognitive dysfunction. With only one FDA-approved therapy, effective treatment …