Systematic reviews can help practitioners keep abreast of the medical literature by
summarizing large bodies of evidence and helping to explain differences among studies on …

Systematic reviews can help practitioners keep abreast of the medical literature by
summarizing large bodies of evidence and helping to explain differences among studies on …

With more than 2 million articles published annually in over 20,000 biomedical journals,
Systematic Reviews is a valuable guide to assembling and using the best available medical …

Successful clinical decisions, like most human de-cisions, are complex creatures (1). In
making them, we draw on information from many sources: primary data and patient …

Much time and effort are spent on designing primary research studies. Similar care must be
given to planning systematic reviews. The review should be based on an important, well …

After thoroughly searching the potentially relevant literature for a systematic review,
reviewers face the sequential tasks of selecting studies for inclusion and appraising these …

Healthcare decisions for individual patients and for public health policies should be
informed by the best available research evidence. The practice of evidence-based medicine …

Clinical decisions should be based on the totality of the best evidence and not the results of
individual studies. When clinicians apply the results of a systematic review or meta-analysis …

What do we do if different studies appear to give different answers? When applying research
to questions for individual patients or for health policy, one of the challenges is interpreting …

Clinical practice guidelines have been developed to improve the process and outcomes of
health care and to optimize resource utilization. By addressing such issues as prevention …