Copper (II) complexes of phenanthroline and histidine containing ligands: Synthesis, characterization and evaluation of their DNA cleavage and cytotoxic activity

SMG Leite, LMP Lima, S Gama, F Mendes… - Inorganic …, 2016 - ACS Publications
Copper (II) complexes have been intensely investigated in a variety of diseases and
pathological conditions due to their therapeutic potential. The development of these …

Mixed ligand copper (II) complexes of 2, 9-dimethyl-1, 10-phenanthroline: Tridentate 3N primary ligands determine DNA binding and cleavage and cytotoxicity

M Ganeshpandian, S Ramakrishnan… - Journal of inorganic …, 2014 - Elsevier
A series of mononuclear mixed ligand copper (II) complexes of the type [Cu (L)(2, 9-
dmp)](ClO 4) 2 1–4, where L is a tridentate 3N ligand such as diethylenetriamine (L1)(1) or …

Mixed-ligand copper (II)-phenolate complexes: structure and studies on DNA/protein binding profiles, DNA cleavage, molecular docking and cytotoxicity

S Kathiresan, S Mugesh, M Murugan, F Ahamed… - RSC …, 2016 - pubs.rsc.org
Copper (II) complexes with simple and mixed ligands,[Cu (L)(ClO4)](1) and [Cu (L)(diimine)]
ClO4 (2–4)[where L is 4-chloro-2-((2-(phenylthio) phenylimino) methyl) phenol and diimine …

Design, synthesis, ligand's scaffold variation and structure elucidation of Cu (II) complexes; in vitro DNA binding, morphological studies and their anticancer activity

S Yousuf, F Arjmand, S Tabassum - Polyhedron, 2021 - Elsevier
Two new copper (II) complexes, Cu [(L) 2 (X)](1) and Cu [(L)(X) 2](2) where L= 1, 10-
phenanthroline and X=(2-pyrimidylthio)-acetic acid (PTAA), have been synthesized and …

Copper (II) complexes of 1, 10-phenanthroline-derived ligands: studies on DNA binding properties and nuclease activity

T Hirohama, Y Kuranuki, E Ebina, T Sugizaki… - Journal of Inorganic …, 2005 - Elsevier
A series of copper (II) complexes of the type [Cu (L)] 2+, where L= N, N′–dialkyl-1, 10-
phenanthroline-2, 9-dimethanamine and R= methyl (L1), n-propyl (L2), isopropyl (L3), sec …

Synthesis, DNA binding and docking studies of copper (II) complexes containing modified phenanthroline ligands

J Lakshmipraba, S Arunachalam… - Journal of …, 2015 - Taylor & Francis
Copper (II) complexes,[Cu (Hsal)(L)(ClO4)](where Hsal= salicylaldehyde, 1: L= dpqC=
dipyrido [3, 2-a: 2′, 3′-c](6, 7, 8, 9-tetrahydro) phenazine and 2: L= dppz= dipyrido [3, 2-a …

Synthesis, X-ray crystal structure, DNA/BSA binding, DNA cleavage and cytotoxicity studies of phenanthroline based copper (II)/zinc (II) complexes

Q Wang, H Mao, W Wang, H Zhu, L Dai, Y Chen… - BioMetals, 2017 - Springer
Abstract Research on copper II 1, 10-phenanththroline (phen) derivatives continues to attract
interest in the context of structure and biological properties. In this paper, two metal …

Mixed ligand copper (II) complexes of 1, 10-phenanthroline with tridentate phenolate/pyridyl/(benz) imidazolyl Schiff base ligands: Covalent vs non-covalent DNA …

C Rajarajeswari, M Ganeshpandian… - Journal of inorganic …, 2014 - Elsevier
A series of copper (II) complexes of the types [Cu (L)(phen)](ClO 4) 1–2, where HL is a
tridentate ligand with two nitrogen and one oxygen donor atoms (2NO) such as 2-(2-(1H …

Cytotoxic copper (II) mixed ligand complexes: Crystal structure and DNA cleavage activity

VM Manikandamathavan, RP Parameswari… - European journal of …, 2011 - Elsevier
Two new mixed ligand complexes of copper (II) containing an imidazolyl terpyridine
ligand,[Cu (Itpy)(bpy)](ClO4) 2·(H2O), 1, and [Cu (Itpy)(phen)(ClO4)](ClO4)·(H2O), 2 have …

Synthesis and crystal structures of novel copper (II) complexes with glycine and substituted phenanthrolines: reactivity towards DNA/BSA and in vitro cytotoxic and …

D İnci, R Aydın, Ö Vatan, T Sevgi, D Yılmaz… - JBIC Journal of …, 2017 - Springer
New copper (II) complexes—dimeric-[Cu (nphen)(gly)(H 2 O)]+(1) and [Cu
(dmphen)(gly)(NO 3)(H 2 O)](2)(nphen= 5-nitro-1, 10-phenanthroline, dmphen= 4, 7 …