Estimation of the causal effect of a time-varying exposure on the marginal mean of a repeated binary outcome

JM Robins, S Greenland, FC Hu - Journal of the American …, 1999 - Taylor & Francis
We provide sufficient conditions for estimating from longitudinal data the causal effect of a
time-dependent exposure or treatment on the marginal probability of response for a …

Longitudinal data analysis for discrete and continuous outcomes

SL Zeger, KY Liang - Biometrics, 1986 - JSTOR
Longitudinal data sets are comprised of repeated observations of an outcome and a set of
covariates for each of many subjects. One objective of statistical analysis is to describe the …

Fixed effects, random effects and GEE: What are the differences?

JC Gardiner, Z Luo, LA Roman - Statistics in medicine, 2009 - Wiley Online Library
For analyses of longitudinal repeated‐measures data, statistical methods include the
random effects model, fixed effects model and the method of generalized estimating …

Statistical analysis of correlated data using generalized estimating equations: an orientation

JA Hanley, A Negassa, MDB Edwardes… - American journal of …, 2003 - academic.oup.com
The method of generalized estimating equations (GEE) is often used to analyze longitudinal
and other correlated response data, particularly if responses are binary. However, few …

Causal inference for complex longitudinal data: the continuous case

RD Gill, JM Robins - Annals of Statistics, 2001 - JSTOR
We extend Robins' theory of causal inference for complex longitudinal data to the case of
continuously varying as opposed to discrete covariates and treatments. In particular we …

gformula: Estimating causal effects in the presence of time-varying confounding or mediation using the g-computation formula

RM Daniel, BL De Stavola, SN Cousens - The Stata Journal, 2011 - journals.sagepub.com
This article describes a new command, gformula, that is an implementation of the g-
computation procedure. It is used to estimate the causal effect of time-varying exposures on …

Methods for dealing with time‐dependent confounding

RM Daniel, SN Cousens, BL De Stavola… - Statistics in …, 2013 - Wiley Online Library
Longitudinal studies, where data are repeatedly collected on subjects over a period, are
common in medical research. When estimating the effect of a time‐varying treatment or …

Models for longitudinal data: a generalized estimating equation approach

SL Zeger, KY Liang, PS Albert - Biometrics, 1988 - JSTOR
This article discusses extensions of generalized linear models for the analysis of
longitudinal data. Two approaches are considered: subject-specific (SS) models in which …

Implementation of G-computation on a simulated data set: demonstration of a causal inference technique

JM Snowden, S Rose… - American journal of …, 2011 - academic.oup.com
The growing body of work in the epidemiology literature focused on G-computation includes
theoretical explanations of the method but very few simulations or examples of application …

Marginal structural models and causal inference in epidemiology

JM Robins, MA Hernan, B Brumback - Epidemiology, 2000 - journals.lww.com
In observational studies with exposures or treatments that vary over time, standard
approaches for adjustment of confounding are biased when there exist time-dependent …