The tachykinins comprise a family of closely related peptides that participate in the
regulation of diverse biological processes. The tachykinin peptides substance P, neurokinin …

The peptides of the tachykinin family are widely distributed within the mammalian peripheral
and central nervous systems and play a well-recognized role as excitatory …

The existence of multiple mammalian tachykinins is now well established (for recent reviews
see 1-4). In addition to substance P (SP), mammalian tachykinins include neurokinin A …

Tachykinins exert a broad range of actions in the mammalian nervous system. While much is
known about the localization of peptides derived from one of the two mammalian tachykinin …

Tachykinins belong to an evolutionarily conserved family of peptide neurotransmitters. The
mammalian tachykinins include substance P, neurokinin A and neurokinin B, which exert …

Neuropeptides and other biologically active peptides exhibit a high degree of functional di
versi ty wi thin the same group of peptides not only through the regulation of peptide …

Throughout the past decade, major advances have been made in our understanding of the
biology of the mammalian tachykinin neuropeptides. It is now well established that …

There is an expanding repertoire of mammalian tachykinins produced by a variety of
tachykinin genes, gene splicing events and peptide processing. Novel tachykinin-binding …

Quantitative receptor autoradiography using several radiolabeled tachykinins was used to
localize and characterize tachykinin peptide receptor binding sites in rat CNS and peripheral …

The tachykinin family has recently been extended by the discovery of a third tachykinin gene
encoding previously unknown mammalian tachykinins (hemokinin 1, endokinin A and …