Diffuse large B-cell lymphoma

S Li, KH Young, LJ Medeiros - Pathology, 2018 - Elsevier
Diffuse large B cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma
worldwide, representing approximately 30–40% of all cases in different geographic regions …

[HTML][HTML] Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive review

R Camicia, HC Winkler, PO Hassa - Molecular cancer, 2015 - Springer
Diffuse large B-cell lymphoma (DLBCL) is a clinically heterogeneous lymphoid malignancy
and the most common subtype of non-Hodgkin's lymphoma in adults, with one of the highest …

Young patients with non–germinal center B-cell–like diffuse large B-cell lymphoma benefit from intensified chemotherapy with ACVBP plus rituximab compared with …

TJ Molina, D Canioni, C Copie-Bergman… - Journal of clinical …, 2014 - ascopubs.org
Purpose To determine whether any tumor biomarkers could account for the survival
advantage observed in the LNH 03-2B trial among patients with diffuse large B-cell …

[HTML][HTML] CD5 expression is potentially predictive of poor outcome among biomarkers in patients with diffuse large B-cell lymphoma receiving rituximab plus CHOP …

D Ennishi, K Takeuchi, M Yokoyama, H Asai… - Annals of oncology, 2008 - Elsevier
Background Several biomarkers indicating poor prognosis have been reassessed in
patients receiving rituximab combination chemotherapy for diffuse large B-cell lymphoma …

[HTML][HTML] MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavorable prognosis

JS Vermaat, SF Somers, LC de Wreede, W Kraan… - …, 2020 - ncbi.nlm.nih.gov
Abstract The 2016 World Health Organization classification defines diffuse large B-cell
lymphoma (DLBCL) subtypes based on Epstein-Barr virus (EBV) infection and oncogenic …

[HTML][HTML] C-MYC aberrations as prognostic factors in diffuse large B-cell lymphoma: a meta-analysis of epidemiological studies

K Zhou, D Xu, Y Cao, J Wang, Y Yang, M Huang - PloS one, 2014 - journals.plos.org
Objectives Various studies have investigated the prognostic value of C-MYC aberrations in
diffuse large B-cell lymphoma (DLBCL). However, the role of C-MYC as an independent …

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma

A Rosenwald, G Wright, WC Chan… - … England Journal of …, 2002 - Mass Medical Soc
Background The survival of patients with diffuse large-B-cell lymphoma after chemotherapy
is influenced by molecular features of the tumors. We used the gene-expression profiles of …

Gene expression profiling of diffuse large B-cell lymphoma

A Rosenwald, LM Staudt - Leukemia & lymphoma, 2003 - Taylor & Francis
Initial gene expression profiling studies of diffuse large B-cell lymphoma (DLBCL) revealed
that this single diagnosis actually encompasses two distinct diseases that differ in the …

ROBUST: lenalidomide-R-CHOP versus placebo-R-CHOP in previously untreated ABC-type diffuse large B-cell lymphoma

GS Nowakowski, A Chiappella, TE Witzig… - Future …, 2016 - Taylor & Francis
Activated B-cell-like (ABC) diffuse large B-cell lymphoma (DLBCL), the major constituent of
nongerminal center B-cell-like (non-GCB) DLBCL, is associated with poorer survival …

Prognostic significance of Bcl-6 protein expression in DLBCL treated with CHOP or R-CHOP: a prospective correlative study

JN Winter, EA Weller, SJ Horning, M Krajewska… - Blood, 2006 - ashpublications.org
Bcl-6 protein expression, a marker of germinal center origin, has been associated with a
favorable prognosis in diffuse large B-cell lymphoma (DLBCL). To determine the prognostic …