Background The oestrogen receptor beta (ERβ) is the predominant oestrogen receptor in
the normal colon mucosa and has been reported to exert anti-proliferative and pro-apoptotic …

Background: Previous studies suggest that sex steroids influence colorectal cancer (CRC)
carcinogenesis. The oestrogen receptor β (ERβ) is the predominantly expressed ER in the …

We reported that high estrogen receptor beta (ERβ) expression is independently associated
with better prognosis in female colorectal cancer (CRC) patients. However, estrogen …

Background Estrogen receptor β (ERβ) is a potential tumor-suppressor gene in colorectal
cancer (CRC). This hypothesis is supported by clinical and laboratory observations. Aim In …

Gender differences in the incidence and behaviour of colon cancer suggest a hormonal
influence and epidemiological data suggest a protective effect for hormone replacement …

Oestrogen Receptor β (ERβ) may protect against prostate and mammary cell proliferation
and malignant transformation. Epidemiological studies indicate that oestrogens may reduce …

Oestrogen receptor β (ERβ) has been suggested to have anti‐proliferative and anti‐tumour
effects in breast and prostate cancer cells, but other studies have indicated its tumour …

Background Among the sex hormones, oestrogen may play a role in colorectal cancer,
particularly in conjunction with oestrogen receptor-β (ERβ). The expression of ERβ isoform …

Colorectal cancer (CRC) is one of the most common types of malignancy with high morbidity
and mortality rates worldwide. This biologically heterogeneous disease results in diverse …

Several strands of evidence indicate that oestrogens exert a protective role against the
development of colon cancer through indirect and direct effects on colonic epithelium …