Rationale Despite the potentially important roles for infection in adult non-cystic fibrosis (CF)
bronchiectasis disease progression, the bacterial species present in the lower airways of …

Background Chronic airway infection contributes to the underlying pathogenesis of non-
cystic fibrosis bronchiectasis (NCFBr). In contrast to other chronic airway infections …

A diverse microbiota exists within the airways of individuals with non-cystic fibrosis
bronchiectasis (nCFB). How the lung microbiome evolves over time, and whether changes …

Rationale: Although airway microbiota composition correlates with clinical measures in non–
cystic fibrosis bronchiectasis, these data are unlikely to provide useful prognostic information …

Our objectives were to characterise the microbiota in cystic fibrosis (CF) bronchoalveolar
lavage fluid (BALF), and determine its relationship to inflammation and disease status. BALF …

Background Molecular-based diagnostic techniques can compensate for the inherent
limitations of culture-based microbiology and provide a more comprehensive description of …

Background Culture-independent analysis of the respiratory secretions of people with cystic
fibrosis (CF) has identified many bacterial species not previously detected using culture in …

Cystic fibrosis (CF) is a genetic disease resulting in chronic polymicrobial infections of the
airways and progressive decline in lung function. To gain insight into the underlying causes …

Cystic fibrosis (CF) is characterized by defective mucociliary clearance and chronic airway
infection by a complex microbiota. Infection, persistent inflammation and periodic episodes …

Bacterial communities in the airways of cystic fibrosis (CF) patients are, as in other
ecological niches, influenced by autogenic and allogenic factors. However, our …