Cancer cachexia is a muscle-wasting syndrome that leads to a severely compromised
quality of life and increased mortality. A strong association between cachexia and poor …

Cancer cachexia is a multifactorial syndrome characterized by anorexia, weight loss and
muscle wasting that impairs patients' quality of life and survival. Aim of this work was to …

Cancer-associated cachexia is a complex metabolic condition characterized by the
progressive loss of body fat and deterioration of muscle mass. Although the cellular and …

Simple Summary Chronic disease-related muscle atrophy is a serious public health problem
since it reduces mobility and contributes to increases in hospitalization costs. Unfortunately …

Background Cachexia is a complex metabolic disorder and muscle atrophy syndrome,
impacting 80% patients with advanced cancers. Malignant glioma is considered to be one of …

Background Cachexia is a debilitating complication of cancer characterized by progressive
wasting and weakness of skeletal muscles that reduces quality of life and can compromise …

Background Muscle wasting during cancer cachexia contributes to patient morbidity.
Cachexia‐induced muscle damage may be understood by comparing its symptoms with …

Abstract Muscle atrophy F-Box (MAFbx)/atrogin-1 and muscle ring-finger-1 (MuRF-1) have
been identified as two muscle-specific E3 ubiquitin ligases that are highly expressed in …

Muscle atrophy is a major character of cancer cachexia, whose mechanism remains
enigmatic. During cancer cachexia, the function of endoplasmic reticulum stress (ERS) …

Cancer cachexia (CC) accounts for 20%–40% of cancer-related deaths. Mitochondrial
aberrations have been shown to precede muscle atrophy in different atrophy models …