The advent of organic synthesis and the understanding of the molecule as they occurred in
the nineteenth century and were refined in the twentieth century constitute two of the most …

The Chemistry of Heterocycles: Chemistry of Six to Eight Membered N, O, S, P and Se
Heterocycles details the chemistry, behavior and potential of these important structures. The …

Tailor-made AAs are indispensable components of modern medicinal chemistry and are
becoming increasingly prominent in new drugs. In fact, about 30% of small-molecule …

Diagnostics and therapeutics are generally separate entities in medicine. Theranostics,
agents that provide for both modalities, are being developed. However, they often require …

Strained ring systems have gained considerable importance over the last few years for their
implication in natural product syntheses or in drug discovery programs. We present herein a …

New methods are urgently needed to find novel natural products as structural leads for the
development of new drugs against emerging diseases such as cancer and multiresistant …

Amino acids, the building blocks of proteins, also serve as precursors to a wide range of
other naturally occurring substances including alkaloids, antibiotics, and, the subject of this …

The nitrogen–nitrogen bond is a core feature of diverse functional groups like hydrazines,
nitrosamines, diazos, and pyrazoles. Such functional groups are found in> 300 known …

Functionalised azepane and oxepane scaffolds were prepared using diazocarbonyl
chemistry and elaborated to show their potential use in library synthesis. Key dicarbonyl …

The assembly of a wide range of dialkylzincs, cyclic enones, and chiral N-tert-butylsulfinyl
imines in the presence of the appropriate phosphoramidite ligands allowed the formation of …