Fabrication of carboxymethylcellulose-gelatin dissolving microneedle patch for pain-free, efficient, and controlled transdermal delivery of insulin
BA Jana, RA Osmani, S Jaiswal, R Banerjee… - Journal of …, 2023 - Springer
Purpose Dissolving microneedle patches are attracting attention as they are associated with
improved patient compliance and safety. Methods This study fabricated dissolving …
improved patient compliance and safety. Methods This study fabricated dissolving …
Innovative freeze-drying technique in the fabrication of dissolving microneedle patch: Enhancing transdermal drug delivery efficiency
T Su, Z Tang, J Hu, Y Zhu, T Shen - Drug Delivery and Translational …, 2024 - Springer
Microneedle patch (MNP) has become a hot research topic in the field of transdermal drug
delivery due to its ability to overcome the stratum corneum barrier. Among the various types …
delivery due to its ability to overcome the stratum corneum barrier. Among the various types …
Formulation of two‐layer dissolving polymeric microneedle patches for insulin transdermal delivery in diabetic mice
Dissolving microneedles (MNs) display high efficiency in delivering poorly permeable drugs
and vaccines. Here, two‐layer dissolving polymeric MN patches composed of gelatin and …
and vaccines. Here, two‐layer dissolving polymeric MN patches composed of gelatin and …
Dissolving microneedle rollers for rapid transdermal drug delivery
Dissolving microneedle patch (DMNP) is a minimally invasive and painless self-
administration device. However, due to skin deformation, it is difficult to apply it on the large …
administration device. However, due to skin deformation, it is difficult to apply it on the large …
Implantable powder-carrying microneedles for transdermal delivery of high-dose insulin with enhanced activity
Recently, numerous transdermal drug delivery systems have been developed for safe and
efficient delivery of biopharmaceuticals. Dissolving microneedles (DMNs) are one such drug …
efficient delivery of biopharmaceuticals. Dissolving microneedles (DMNs) are one such drug …
[HTML][HTML] Dissolving polymer microneedles for transdermal delivery of insulin
N Zhang, X Zhou, L Liu, L Zhao, H Xie… - Frontiers in …, 2021 - frontiersin.org
It's of great significance to develop insulin-loaded dissolving microneedles (MNs) which are
fabricated with various methods and materials for transdermal delivery of insulin to …
fabricated with various methods and materials for transdermal delivery of insulin to …
[HTML][HTML] Dissolving microneedle patches for transdermal insulin delivery in diabetic mice: potential for clinical applications
CH Chen, VBH Shyu, CT Chen - Materials, 2018 - mdpi.com
In this study, dissolving polymeric microneedle (MN) patches composed of gelatin and
sodium carboxymethyl cellulose (CMC) were used to localize insulin. Their in vitro skin …
sodium carboxymethyl cellulose (CMC) were used to localize insulin. Their in vitro skin …
Practicality of non-invasive glucagon-loaded dissolving microneedle for life-saving treatment of severe hypoglycemia in a diabetic rat model
X Wang, Y Ma, X Qi, X Ruan, D Cao, F Zhao - International Journal of …, 2023 - Elsevier
The development of dissolving microneedles (DMNs) has brought light to the transdermal
delivery of biomolecules that are released into the skin through the rapid dissolution of the …
delivery of biomolecules that are released into the skin through the rapid dissolution of the …
Novel lyophilized hydrogel patches for convenient and effective administration of microneedle-mediated insulin delivery
Y Qiu, G Qin, S Zhang, Y Wu, B Xu, Y Gao - International journal of …, 2012 - Elsevier
A lyophilized hydrogel patch system was developed for microneedle-mediated insulin
delivery. The matrix of Cross-linked poly (acrylamide-co-acrylic acid) were synthesized by …
delivery. The matrix of Cross-linked poly (acrylamide-co-acrylic acid) were synthesized by …
Dissolving polymer microneedle patches for rapid and efficient transdermal delivery of insulin to diabetic rats
MH Ling, MC Chen - Acta biomaterialia, 2013 - Elsevier
This study presents a dissolving microneedle patch, composed of starch and gelatin, for the
rapid and efficient transdermal delivery of insulin. The microneedles completely dissolve …
rapid and efficient transdermal delivery of insulin. The microneedles completely dissolve …
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