In this work, a wide range of novel quinazolin‐4 (3H)‐one linked to 1, 2, 3‐triazoles was
designed, synthesized, and evaluated against a panel of three human breast (MDA‐MB …

New hybrid compounds with functionalized quinazoline derivatives and derived tricyclic
compounds with varied condensed six and five-membered ring systems were synthesized …

For the purpose of developing novel EGFR/HER2 tyrosine kinases inhibitors with high
inhibition activity and low toxicity, two novel series of oxazolo [4, 5-g] quinazolin-2 (1H)-one …

Depending on the pharmacophoric characteristics of EGFR inhibitors, a new thieno [2, 3-d]
pyrimidine derivative has been developed. Firstly, the potential inhibitory effect of the …

This work deals with the design and synthesis of a series of new substituted 2-
arylbenzothiazole compounds attached to 4-oxothiazolidin-2-ylidene ring 2–12 and chain …

A new series of bis ([1, 2, 4] triazolo)[4, 3-a: 3′, 4′-c] quinoxaline derivatives were
designed and synthesized to have the main essential pharmacophoric features of VEGFR-2 …

New benzothiazole-based derivatives were synthesized in the present work with the aim of
evaluating their antitumor activity. They were in vitro tested against hepatocellular carcinoma …

This study reports design and synthesis of thirteen pyrido [2, 3-d] pyrimidin-4 (3H)-one
derivatives as EGFR inhibitors. The antiproliferation activities were tested for all compounds …

A new series of pyridothienopyrimidine derivatives was designed and evaluated as
antimicrobial and anticancer agents. The target compounds were synthesized starting with 3 …

Herein, the design, synthesis and mechanistic study of five series of imidazo [1, 2-a]
pyridines 8a-d, 9a-f, 11a-c, 12a-d and 14a-d as anticancer agents were discussed. The …