BACKGROUND: Recent studies on the association between vitamin A and fracture risk have
focused on samples with high vitamin A intake. We analyzed a cohort that was more …

Excessive intake of vitamin A is postulated to have a detrimental effect on bone by inducing
osteoporosis. This may lead to an increased risk of fracture, particularly in persons who are …

Background Excessive intakes of vitamin A have been shown to have adverse skeletal
effects in animals. High vitamin A intake may lead to an increased risk of fracture in humans …

ContextIngestion of toxic amounts of vitamin A affects bone remodeling and can have
adverse skeletal effects in animals. The possibility has been raised that long-term high …

Background: The highest incidence of osteoporotic fractures is found in northern Europe,
where dietary intake of vitamin A (retinol) is unusually high. In animals, the most common …

In recent studies from Sweden and the United States, a high vitamin A intake has been
associated with low bone mineral density (BMD) and increased fracture risk. In Sweden and …

Osteoporotic fracture is a significant cause of morbidity and mortality and is a challenging
global health problem. Previous reports of the relation between vitamin A intake or blood …

There is debate about the possible deleterious effect of excessive vitamin A exposure on
fracture risk. In this nested case control study in older women (312 cases and 934 controls) …

VITAMIN A, an essential micronutrient, is provided by animal foods, whereas-carotene and
other carotenoids, known as provitamin A molecules, are derived from plant sources. In …

Background Although studies in animals and epidemiologic studies have indicated that a
high vitamin A intake is associated with increased bone fragility, no biologic marker of …