[HTML][HTML] High-density lipoprotein: a double-edged sword in cardiovascular physiology and pathophysiology

G Ndrepepa - Journal of Laboratory and Precision Medicine, 2021 - jlpm.amegroups.org
High-density lipoprotein (HDL) plays a central role in vascular biology. HDL participates in
multiple pathways that may be involved in the development of atherosclerosis and coronary …

[HTML][HTML] Thematic review series: High density lipoprotein structure, function, and metabolism: High density lipoproteins and endothelial functions: Mechanistic insights …

M Riwanto, U Landmesser - Journal of Lipid Research, 2013 - ncbi.nlm.nih.gov
Prospective population studies in the primary prevention setting have shown that reduced
plasma levels of HDL cholesterol are associated with an increased risk of coronary disease …

High-density lipoprotein: vascular protective effects, dysfunction, and potential as therapeutic target

TF Lüscher, U Landmesser, A von Eckardstein… - Circulation …, 2014 - Am Heart Assoc
High-density lipoprotein (HDL) is a complex mixture of lipoproteins that is associated with
many minor proteins and lipids that influence the function of HDL. Although HDL is a …

[PDF][PDF] Dysfunctional HDL: from structure-function-relationships to biomarkers

M Riwanto, L Rohrer, A von Eckardstein… - High Density …, 2015 - library.oapen.org
Reduced plasma levels of HDL-C are associated with an increased risk of CAD and
myocardial infarction, as shown in various prospective population studies. However, recent …

Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis

A Kontush, MJ Chapman - Pharmacological reviews, 2006 - ASPET
High-density lipoproteins (HDL) possess key atheroprotective biological properties,
including cellular cholesterol efflux capacity, and anti-oxidative and anti-inflammatory …

[HTML][HTML] High-Density Lipoproteins and Cardiovascular Disease: The Good, the Bad and the Future

J Julve, JC Escolà-Gil - Biomedicines, 2021 - mdpi.com
Epidemiological studies have shown that low levels of plasma high-density lipoprotein
cholesterol (HDL-C) are associated with increased atherosclerotic cardiovascular disease …

High-density lipoprotein: epidemiology, metabolism, and antiatherogenic effects

PP Toth - Disease-a-month, 2001 - Elsevier
Conclusion HDL is clearly a functionally versatile molecule mediating a variety of molecular
processes protective against atherosclerosis. Mechanistic detail continues to greatly enrich …

Novel insights from human studies on the role of high-density lipoprotein in mortality and noncardiovascular disease

CM Madsen, A Varbo… - … , thrombosis, and vascular …, 2021 - Am Heart Assoc
The vast majority of research about HDL (high-density lipoprotein) has for decades revolved
around the possible role of HDL in atherosclerosis and its therapeutic potential within …

High-density lipoprotein (HDL) dysfunction and the future of HDL

S Ertek - Current vascular pharmacology, 2018 - ingentaconnect.com
Although High Density Lipoprotein Cholesterol (HDL-C) levels are inversely proportional to
cardiovascular risk in many studies, recent pharmacological interventional studies with HDL …

High-density lipoproteins: a therapeutic target for atherosclerotic cardiovascular disease

M Gomaraschi, L Calabresi… - Expert Opinion On …, 2006 - Taylor & Francis
Despite great progress being made during the last two decades in cardiovascular disease
prevention, especially by lowering low-density lipoprotein-cholesterol with statins …