Multivalent nanomaterials: learning from vaccines and progressing to antigen-specific immunotherapies

BL Hartwell, L Antunez, BP Sullivan, S Thati… - Journal of …, 2015 - Elsevier
Continued development of multivalent nanomaterials has provided opportunities for the
advancement of antigen-specific immunotherapies. New insights emerge when considering …

[PDF][PDF] Potential of nanocarriers in antigen delivery: the path to successful vaccine delivery

P Prabhu, V Patravale - Nanocarriers, 2014 - researchgate.net
Vaccination has indubitably made noteworthy contribution to global health. Recent years
have witnessed the employment of subunit antigens rather than inactivated or live …

Nanomaterials for antigen-specific immune tolerance therapy

J Park, Y Wu, Q Li, J Choi, H Ju, Y Cai, J Lee… - Drug Delivery and …, 2023 - Springer
Impairment of immune tolerance might cause autologous tissue damage or overactive
immune response against non-pathogenic molecules. Although autoimmune disease and …

Recent advances in nanovaccines using biomimetic immunomodulatory materials

V Vijayan, A Mohapatra, S Uthaman, IK Park - Pharmaceutics, 2019 - mdpi.com
The development of vaccines plays a vital role in the effective control of several fatal
diseases. However, effective prophylactic and therapeutic vaccines have yet to be …

Application of nanotechnologies for improved immune response against infectious diseases in the developing world

M Look, A Bandyopadhyay, JS Blum… - Advanced drug delivery …, 2010 - Elsevier
There is an urgent need for new strategies to combat infectious diseases in developing
countries. Many pathogens have evolved to elude immunity and this has limited the utility of …

Polymer-based nanosystems—A versatile delivery approach

AG Niculescu, AM Grumezescu - Materials, 2021 - mdpi.com
Polymer-based nanoparticles of tailored size, morphology, and surface properties have
attracted increasing attention as carriers for drugs, biomolecules, and genes. By protecting …

Hide and seek: Nanomaterial interactions with the immune system

B Fadeel - Frontiers in immunology, 2019 - frontiersin.org
Engineered nanomaterials hold promise for a wide range of applications in medicine.
However, safe use of nanomaterials requires that interactions with biological systems, not …

Programmable Bionanomaterials for revolutionizing cancer immunotherapy

A Sharma, DD Bhatia - Biomaterials Science, 2024 - pubs.rsc.org
Cancer immunotherapy involves a cutting-edge method that utilizes the immune system to
detect and eliminate cancer cells. It has shown substantial effectiveness in treating different …

Nanoparticles for immune stimulation against infection, cancer, and autoimmunity

S Singha, K Shao, KK Ellestad, Y Yang, P Santamaria - ACS nano, 2018 - ACS Publications
Vaccination using nanocarrier-based delivery systems has recently emerged as a promising
approach for meeting the continued challenge posed by infectious diseases and cancer. A …

Polymeric micro-and nanoparticles for immune modulation

E Ben-Akiva, SE Witte, RA Meyer, KR Rhodes… - Biomaterials …, 2019 - pubs.rsc.org
New advances in biomaterial-based approaches to modulate the immune system are being
applied to treat cancer, infectious diseases, and autoimmunity. Particulate systems are …