To the Editor: Since 2003, outbreaks of Clostridium difficile–associated disease (CDAD)
associated with the emergence of a hypervirulent strain have been reported worldwide (1, 2; …

Clostridium difficile infection (CDI) is the major cause of nosocomial diarrhea, associated
with increased morbidity and mortality, prolonged duration of hospital admissions, and …

3. Of those who received any treatment (metronidazole or vancomycin or both) and a PPI,
the relapse rate was 33.8%(68/201), compared to 21.7%(123/568) for those who did not …

To the Editor—Clostridium difficile has been a predominant cause of nosocomial diarrhea in
North America and Europe, especially after the emergence of PCR-ribotypes 027 and 078 …

Further to the recent publication in CMI of a European survey characterising Clostridium
difficile isolates in Europe [1], we would like to report the occurrence of a small outbreak …

Objectives To investigate an unusual outbreak of five patients with a total of eight episodes
of a Clostridium difficile infection on a gastrointestinal surgical ward of a Dutch tertiary-care …

A new, hypervirulent strain of Clostridium difficile, called NAP1/BI/027, has been implicated
in C. difficile outbreaks associated with increased morbidity and mortality since the early …

The purpose of this study was to identify clinical characteristics of Clostridium difficile
infection (CDI) in patients with antibiotic-associated diarrhea (AAD). A prospective study was …

Abstract Background Clostridioides (Clostridium) difficile infection (CDI) has become an
increasingly significant disease not only as healthcare-associated infection, but also as …

Clostridium difficile is the aetiological agent in ca. 20% of cases of antimicrobial-associated
diarrhoea in hospitalised adults. Diseases caused by this organism range from mild …