Management of unfit older patients with advanced NSCLC

C Gridelli, P Maione, A Rossi, G Palazzolo… - Cancer Treatment …, 2009 - Elsevier
Lung cancer in the older individual is an increasingly common problem faced by the
oncologist. Elderly patients over 70years account about 40% of lung cancer patients …

Medical treatment of advanced non-small cell lung cancer in elderly patients: a review of the role of chemotherapy and targeted agents

G Meoni, FL Cecere, E Lucherini… - Journal of geriatric …, 2013 - Elsevier
Lung cancer is the leading cause of cancer related mortality worldwide. Non-small cell lung
cancer (NSCLC) accounts for 85% of all cases. Half of the patients at diagnosis of NSCLC …

Cost analysis of erlotinib versus chemotherapy for first-line treatment of non–small-cell lung cancer in frail elderly patients participating in a prospective phase 2 study …

C Chouaid, H Le Caer, R Corre, J Crequit, C Locher… - Clinical Lung Cancer, 2013 - Elsevier
Background A large proportion of elderly patients (> 70 years) with newly diagnosed NSCLC
are shown to be frail by a comprehensive geriatric assessment. This population is more …

Treating advanced non-small cell lung cancer in the elderly

P Maione, A Rossi, PC Sacco… - … in medical oncology, 2010 - journals.sagepub.com
More than 40% of cases of all lung cancers are diagnosed in patients over the age of 70
years. Elderly patients have more comorbidities and tend to be less tolerant to toxic medical …

Comparison of single-agent chemotherapy and targeted therapy to first-line treatment in patients aged 80 years and older with advanced non-small-cell lung cancer

Q Zhang, Z Wang, J Guo, L Liu, X Han, M Li… - OncoTargets and …, 2015 - Taylor & Francis
Purpose The aim of this study was to compare single-agent chemotherapy with targeted
therapy in initial treatment and to explore a better choice of treatment for patients aged 80 …

[HTML][HTML] Chemotherapy of advanced non-small cell lung cancer in elderly patients

A Rossi, C Gridelli - Annals of oncology, 2006 - Elsevier
Non-small cell lung cancer (NSCLC) may be considered typical of advanced age. More than
50% of NSCLC patients are diagnosed over the age of 65 and approximately one-third of all …

Similar survival rates with first-line gefitinib, gemcitabine, or docetaxel in a randomized phase II trial in elderly patients with advanced non-small cell lung cancer and a …

G Des Guetz, T Landre, V Westeel, B Milleron… - Journal of geriatric …, 2015 - Elsevier
Objectives We evaluated the impact of age in a randomized phase II trial that compared
three first-line drugs in elderly patients with advanced non-small cell lung cancer (NSCLC) …

Treatment of older patients with advanced non-small cell lung cancer: a challenge

L Decoster, D Schallier - Journal of Geriatric Oncology, 2019 - Elsevier
With a median age of 70 years at diagnosis, lung cancer is a disease of older persons. As a
consequence oncologists are confronted with an increasing older lung cancer population for …

Management of the elderly patient with advanced non‐small cell lung cancer

KA Cheong, K Chrystal… - International journal of …, 2006 - Wiley Online Library
Non‐small cell lung cancer (NSCLC) is the most lethal of the common solid malignancies. It
is predominantly a disease of the elderly with the median age at diagnosis 68 years …

Optimal pharmacotherapeutic strategies for elderly patients with advanced non-small cell lung cancer

E Quoix - Drugs & aging, 2011 - Springer
Increases in both life expectancy and cancer incidence with age result in a significant rise in
lung cancer rates among elderly patients, with a median age at diagnosis of between 63 and …