Since its initial description as a Th2-cytokine antagonistic to interferon-alpha and
granulocyte-macrophage colony-stimulating factor, many studies have shown various anti …

Interleukin-10 (IL-10) is one of the most important anti-inflammatory cytokine produced
during bacterial infection. Two related phenomena explain the importance of IL-10 …

The generation of an effective immune response against an infection while also limiting
tissue damage requires a delicate balance between pro-and anti-inflammatory responses …

Infection is associated with enhanced production of cytokines, low-molecular-weight
proteins important for the orchestration of inflammatory processes. Research on the role of …

Macrophages play a central role in infections, as a target for pathogens and in activation of
the immune system. Interleukin-10 (IL-10), a cytokine produced by macrophages, is a potent …

Abstract Interleukin-10 (IL-10) is recognized as an anti-inflammatory cytokine that
downmodulates inflammatory immune responses at multiple levels. In innate cells …

IL-10 is an anti-inflammatory cytokine. During infection it inhibits the activity of Th1 cells, NK
cells, and macrophages, all of which are required for optimal pathogen clearance but also …

Interleukin-10 is the most potent anti-inflammatory cytokine yet identified. It has multiple
actions affecting the innate immune system as well as humoral and cellular immune …

Recent studies have documented that the immunoregulatory functions of IL-12 may play a
role in promoting endogenous protective responses during infections and/or contribute to …

Interleukin (IL)-15 is a recently described cytokine that resembles IL-2 in its biological
activities, stimulating natural killer cells, T cells and B cells to proliferate, secrete cytokines …