De novo cholesterol synthesis in three different animal models of diabetes

KR Feingold, SR Lear, AH Moser - Diabetologia, 1984 - Springer
Recent studies have demonstrated that cholesterol synthesis is increased two to threefold in
the intestines of streptozotocin-induced diabetic rats. Cholesterol synthesis in tissues other …

Effect of glucose or fructose feeding on cholesterol synthesis in diabetic Animals

KR Feingold, AH Moser - American Journal of Physiology …, 1985 - journals.physiology.org
Previous studies have demonstrated that cholesterol synthesis is increased twofold in the
small intestines of rats with streptozotocin-induced diabetes. The purpose of the present …

Localization of cholesterol synthesis in the small intestine of diabetic rats

KR Feingold, AH Moser - American Journal of Physiology …, 1984 - journals.physiology.org
Previous studies have demonstrated that cholesterol synthesis is increased twofold in the
small intestine of diabetic animals. The present study demonstrates that the stimulation of …

Contributions of absorbed dietary cholesterol and cholesterol synthesized in small intestine to hypercholesterolemia in diabetic rats

NL Young, D Lopez, D McNamara - Diabetes, 1988 - Am Diabetes Assoc
To determine how insulin deficiency leads to hypercholesterolemia, we examined
cholesterol absorption, synthesis, and utilization in streptozocin-induced diabetic rats fed a …

Intestinal and hepatic cholesterogenesis in hypercholesterolemic dyslipidemia of experimental diabetes in dogs

LK Kwong, KR Feingold, L Peric-Golia, T Le… - Diabetes, 1991 - Am Diabetes Assoc
We previously reported that dog diabetes results in hypercholesterolemia and the
accumulation of a high-density lipoprotein (HDL) subclass, HDL1. Hypercholesterolemic …

Cholesterol metabolism in diabetes mellitus: the role of diet

CD Saudek, NL Young - Diabetes, 1981 - Am Diabetes Assoc
There is extensive evidence that cholesterol metabolism is abnormal in diabetes. Total
plasma cholesterol is elevated, and more subtle indices of sterol homeostasis are also …

Effect of food intake on intestinal cholesterol synthesis in rats

KR Feingold, G Zsigmond, SR Lear… - American Journal of …, 1986 - journals.physiology.org
The mechanism by which diabetes results in an increase in small intestinal cholesterol
synthesis is unknown. Previous studies have demonstrated that limiting food intake prevents …

The effect of diabetes mellitus on sterol synthesis in the intact rat

KR Feingold, MH Wiley, G MacRae, AH Moser… - Diabetes, 1982 - Am Diabetes Assoc
Diabetes mellitus in both humans and animals is characterized by elevations in plasma
cholesterol concentrations. The cause of this hypercholesterolemia is unknown. The present …

Importance of small intestine in diabetic hypercholesterolemia

KR Feingold - Diabetes, 1989 - Am Diabetes Assoc
Numerous studies have demonstrated that poor glycemic control is asssociated with
elevated plasma cholesterol levels in diabetic patients. Experiments have shown that …

The relationship between cholesterol absorption and intestinal cholesterol synthesis in the diabetic rat model

A Gleeson, D Owens, P Collins, A Johnson… - International journal …, 2000 - ncbi.nlm.nih.gov
The chylomicron remnant particle is thought to be particularly atherogenic and we have
previously shown alterations in post-prandial lipoproteins which could contribute to their …