Efficacy and safety of nivolumab in non‐small cell lung cancer with preexisting interstitial lung disease
O Kanai, YH Kim, Y Demura, M Kanai, T Ito… - Thoracic …, 2018 - Wiley Online Library
Background The risk of developing lung cancer is high in patients with interstitial lung
disease (ILD), as few treatment options are available. Immune checkpoint inhibitors (ICI) are …
disease (ILD), as few treatment options are available. Immune checkpoint inhibitors (ICI) are …
A pilot trial of nivolumab treatment for advanced non-small cell lung cancer patients with mild idiopathic interstitial pneumonia
D Fujimoto, T Morimoto, J Ito, Y Sato, M Ito, S Teraoka… - Lung Cancer, 2017 - Elsevier
Introduction Nivolumab has demonstrated efficacy against metastatic non-small cell lung
cancer (NSCLC). However, immune-related adverse events can occur, among which …
cancer (NSCLC). However, immune-related adverse events can occur, among which …
Nivolumab for advanced non-small cell lung cancer patients with mild idiopathic interstitial pneumonia: a multicenter, open-label single-arm phase II trial
D Fujimoto, M Yomota, A Sekine, M Morita, T Morimoto… - Lung Cancer, 2019 - Elsevier
Highlights•Administering nivolumab may challenge NSCLC patients with IIP.•We performed
a multicenter phase-II trial to assess nivolumab's efficacy and safety.•The 6 months PFS rate …
a multicenter phase-II trial to assess nivolumab's efficacy and safety.•The 6 months PFS rate …
Non-inferior clinical outcomes of immune checkpoint inhibitors in non-small cell lung cancer patients with interstitial lung disease
Y Tasaka, T Honda, N Nishiyama, T Tsutsui, H Saito… - Lung Cancer, 2021 - Elsevier
Objectives The efficacy of immune checkpoint inhibitors (ICIs) in non-small-cell lung cancer
(NSCLC) patients with pre-existing interstitial lung disease (ILD) is unclear. Materials and …
(NSCLC) patients with pre-existing interstitial lung disease (ILD) is unclear. Materials and …
Correlation of radiation pneumonitis history before nivolumab with onset of interstitial lung disease and progression-free survival of patients with pre-treated advanced …
A Tamiya, M Tamiya, K Nakahama… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Nivolumab has a promising efficacy for patients with non-small-cell lung
cancer (NSCLC) as second-line or later treatment, and after radiotherapy as abscopal effect …
cancer (NSCLC) as second-line or later treatment, and after radiotherapy as abscopal effect …
Efficacy and safety of nivolumab in previously treated patients with non-small cell lung cancer: a multicenter retrospective cohort study
D Fujimoto, H Yoshioka, Y Kataoka, T Morimoto… - Lung cancer, 2018 - Elsevier
Introduction Nivolumab has been shown to be effective and safe in previously treated
patients with advanced non-small cell lung cancer (NSCLC). However, little is known …
patients with advanced non-small cell lung cancer (NSCLC). However, little is known …
[HTML][HTML] Nivolumab-induced interstitial lung disease analysis of two phase II studies patients with recurrent or advanced non-small-cell lung cancer
T Kato, N Masuda, Y Nakanishi, M Takahashi, T Hida… - Lung cancer, 2017 - Elsevier
Objectives Drug-induced interstitial lung disease (ILD) is often associated with high
mortality; however it is difficult to predict and manage. we examined the clinical findings and …
mortality; however it is difficult to predict and manage. we examined the clinical findings and …
Immune checkpoint inhibitor‐associated interstitial lung diseases correlate with better prognosis in patients with advanced non‐small‐cell lung cancer
T Sugano, M Seike, Y Saito, T Kashiwada… - Thoracic …, 2020 - Wiley Online Library
Background Interstitial lung disease (ILD) induced by immune checkpoint inhibitors (ICIs) is
a potentially life‐threatening adverse event. The purpose of this study was to evaluate …
a potentially life‐threatening adverse event. The purpose of this study was to evaluate …
[HTML][HTML] Nivolumab plus ipilimumab in advanced non–small-cell lung cancer
MD Hellmann, L Paz-Ares… - … England Journal of …, 2019 - Mass Medical Soc
Background In an early-phase study involving patients with advanced non–small-cell lung
cancer (NSCLC), the response rate was better with nivolumab plus ipilimumab than with …
cancer (NSCLC), the response rate was better with nivolumab plus ipilimumab than with …
Real-world efficacy and safety of nivolumab for advanced non–small-cell lung cancer: a retrospective multicenter analysis
K Kobayashi, I Nakachi, K Naoki, R Satomi… - Clinical lung cancer, 2018 - Elsevier
Background Nivolumab, an immune checkpoint inhibitor, is now a standard treatment for
previously treated advanced non–small-cell lung cancer based on the results from phase III …
previously treated advanced non–small-cell lung cancer based on the results from phase III …
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