This study investigated how maternal overnutrition and obesity regulate expression and
activation of proteins that facilitate lipid transport in the placenta. To create a maternal …

Introduction Recent data suggest that in addition to glucose, fetal growth is related to
maternal triglycerides (TG). To reach the fetus, TG must be hydrolyzed to free fatty acids …

Maternal diabetes can cause fetal macrosomia and increased risk of obesity, diabetes, and
cardiovascular disease in adulthood of the offspring. Although increased transplacental lipid …

Obesity in pregnancy is associated with increased fetal growth and adiposity, which, in part,
is determined by transplacental nutrient supply. Trophoblast uptake and intracellular …

Abstract Knowledge of the consequences of maternal obesity in human placental fatty acids
(FA) transport and metabolism is limited. Animal studies suggest that placental uptake of …

Key points Maternal high‐fat diet (MHF) consumption led to metabolic and liver disorders in
male offspring, which are associated with reduced sirtuin (SIRT) 1 expression and activity in …

Advanced maternal age and obesity are the main risk factors to develop gestational
diabetes mellitus (GDM). Obesity is a consequence of the increased storage of …

Metabolic alterations in obese and overweight mothers impact the placenta and the fetus,
leading to anomalies in fetal growth and lipid accretion. The primary aim of the study was to …

Background: Obesity before pregnancy is associated with impaired metabolic status of the
mother and the offspring later in life. These adverse effects have been attributed to …

Context: Obesity and diabetes during pregnancy are associated with increased insulin
resistance and higher neonatal adiposity. In turn, insulin resistance triggers inflammatory …