Roles of oxidative stress in signaling and inflammation induced by particulate matter

F Mazzoli-Rocha, S Fernandes… - Cell biology and …, 2010 - Springer
This review reports the role of oxidative stress in impairing the function of lung exposed to
particulate matter (PM). PM constitutes a heterogeneous mixture of various types of particles …

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

N Li, T Xia, AE Nel - Free radical biology and medicine, 2008 - Elsevier
Ambient particulate matter (PM) is an environmental factor that has been associated with
increased respiratory morbidity and mortality. The major effect of ambient PM on the …

Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10)

K Donaldson, V Stone, PJA Borm, LA Jimenez… - Free Radical Biology …, 2003 - Elsevier
This review focuses on the potential role that oxidative stress plays in the adverse effects of
PM10. The central hypothesis is that the ability of PM10 to cause oxidative stress underlies …

Particulate matter induces tissue oxinflammation: from mechanism to damage

G Valacchi, N Magnani, B Woodby… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Oxidative stress and oxidative damage are central hypothetical mechanisms
for the adverse effects of airborne particulate matter (PM). Activation of inflammatory cells …

Oxidant mechanisms in response to ambient air particles

B González-Flecha - Molecular aspects of medicine, 2004 - Elsevier
The toxic effects of air pollution are widely documented. In recent years, however, there has
been an increasing interest in the study of the health effects of particulate matter (PM), a …

Reactive oxygen species in pulmonary inflammation by ambient particulates

F Tao, B Gonzalez-Flecha, L Kobzik - Free Radical Biology and Medicine, 2003 - Elsevier
Exposure to ambient air pollution particles (PM) has been associated with increased
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …

Fine ambient particles induce oxidative stress and metal binding genes in human alveolar macrophages

YCT Huang, Z Li, JD Carter, JM Soukup… - American journal of …, 2009 - atsjournals.org
Exposure to pollutant particles increased respiratory morbidity and mortality. The alveolar
macrophages (AMs) are one cell type in the lung directly exposed to particles. Upon contact …

[HTML][HTML] Activation of proinflammatory responses in cells of the airway mucosa by particulate matter: oxidant-and non-oxidant-mediated triggering mechanisms

J Øvrevik, M Refsnes, M Låg, JA Holme, PE Schwarze - Biomolecules, 2015 - mdpi.com
Inflammation is considered to play a central role in a diverse range of disease outcomes
associated with exposure to various types of inhalable particulates. The initial mechanisms …

Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues

S Laing, G Wang, T Briazova… - … of physiology-cell …, 2010 - journals.physiology.org
Recent studies have suggested a link between inhaled particulate matter (PM) exposure
and increased mortality and morbidity associated with pulmonary and cardiovascular …

Redox and inflammatory mechanisms linking air pollution particulate matter with cardiometabolic derangements

T Marchini - Free Radical Biology and Medicine, 2023 - Elsevier
Air pollution is the largest environmental risk factor for disease and premature death. Among
the different components that are present in polluted air, fine particulate matter below 2.5 μm …