Transport-dependent anoxic cell injury in the isolated perfused rat kidney.

M Brezis, S Rosen, K Spokes, P Silva… - The American journal of …, 1984 - ncbi.nlm.nih.gov
The hypothesis that decrease in energy demand may prevent anoxic cell damage has been
examined in the medullary thick ascending limb of isolated perfused rat kidneys exposed to …

Disparate mechanisms for hypoxic cell injury in different nephron segments. Studies in the isolated perfused rat kidney.

M Brezis, P Shanley, P Silva, K Spokes… - The Journal of …, 1985 - Am Soc Clin Investig
Hypoxic injury was evaluated morphologically in the proximal tubule and in the medullary
thick ascending limb of isolated rat kidneys perfused for 90 min without O2 or with various …

Intracellular respiratory dysfunction and cell injury in short-term anoxia of rabbit renal proximal tubules.

T Takano, SP Soltoff, S Murdaugh… - The Journal of clinical …, 1985 - Am Soc Clin Investig
The effects of short-term anoxia and hypoxia were studied in a rabbit proximal renal tubule
suspension in order to avoid the hemodynamic consequences of clamp-induced ischemia …

Selective vulnerability of the medullary thick ascending limb to anoxia in the isolated perfused rat kidney.

M Brezis, S Rosen, P Silva… - The Journal of clinical …, 1984 - Am Soc Clin Investig
A specific anatomical lesion sharply localized to the cells of the medullary thick ascending
limbs (mTAL) and characterized by mitochondrial swelling progressing to nuclear pyknosis …

Hypoxic injury in the proximal tubule of the isolated perfused rat kidney

PF Shanley, M Brezis, K Spokes, P Silva, FH Epstein… - Kidney international, 1986 - Elsevier
Hypoxic injury in the proximal tubule of the isolated perfused rat kidney. The effect of
hypoxia on the morphology of the proximal tubule was examined in isolated rat kidneys …

Morphologic and functional evidence for oxygen deficiency in the isolated perfused rat kidney.

HJ Schurek, W Kriz - Laboratory investigation; a journal of technical …, 1985 - europepmc.org
Morphologic and functional studies were undertaken in the isolated rat kidney, perfused with
an albumin-Krebs-Henseleit solution, to which 5% human erythrocytes and/or various amino …

Erythrocytes alter the pattern of renal hypoxic injury: predominance of proximal tubular injury with moderate hypoxia

ZH Endre, PJ Ratcliffe, JD Tange… - Clinical …, 1989 - portlandpress.com
1. The distribution of morphological injury was assessed qualitatively and quantitatively in
the perfused rat kidney in vitro at controlled rates of oxygen delivery in the presence of low …

Topography of focal proximal tubular necrosis after ischemia with reflow in the rat kidney.

PF Shanley, MD Rosen, M Brezis, P Silva… - The American journal …, 1986 - ncbi.nlm.nih.gov
The topography of renal injury after ischemia-reflow was studied in intact rats by clamping
the right renal artery for variable periods of time and examining the histologic appearance of …

Oxygen deprivation-induced injury to isolated rabbit kidney tubules.

JM Weinberg - The Journal of clinical investigation, 1985 - Am Soc Clin Investig
The utility of freshly isolated suspensions of rabbit tubules enriched in proximal segments for
studying the pathogenesis of oxygen deprivation-induced renal tubular cell injury was …

Decrease in renal perfusion, glomerular filtration and sodium excretion by hypoxia in the dog

FJ Bruns - Proceedings of the Society for Experimental …, 1978 - journals.sagepub.com
Previous studies of hypoxia induced alterations in renal function have yielded conflicting
results. Uncontrolled acid base conditions in most studies may account for this scatter. To …