Background and Objective: Tuberculosis (TB) is a devastating infectious disease causing
high mortality and morbidity worldwide. The most serious threat related to tuberculosis …

Background: Prevention and treatment of drug-resistant clones is important in guiding TB
control strategies. The simultaneous rapid detection of the type of mutation conferring …

The aim of this study was to investigate the frequency, location and type of RPOB GENE
MUTATION s in Mycobacterium TUBERCULOSIS (MTB) collected from patients in the …

Background Rifampicin (RIF) plays a pivotal role in the treatment of tuberculosis due to its
bactericidal effects. Because the action of RIF is on rpoB gene encoding RNA polymerase β …

SETTING: The incidence of multi-and extensively drug-resistant TB cases is increasing in
many countries. Resistance to rifampicin is widely considered a surrogate marker for …

Summary Background: Multiple Drug Resistant Tuberculosis (MDR-TB) is increasing
because of widespread application and results in selection of mutants resistant to other …

Background & objectives: Multidrug resistant (MDR) tuberculosis (TB) is a problem of
increasing importance in the world due to limited treatment options. Resistance to rifampicin …

Methods: In this study, 88 Mycobacterium tuberculosis positive samples were included from
Qaem Hospital, Mashhad. MAS-PCR was used to detect the rifampin resistance associated …

Here, we aimed to determine the susceptibility of 70 Mycobacterium tuberculosis isolates
obtained from different regions of the country to 8 anti-tuberculosis (anti-TB) drugs and …

Objectives Ninety-six percent of rifampicin resistance in Mycobacterium tuberculosis was
shown to be associated with mutations inside the 81 bp rifampicin resistance-determining …