The non-steroidal anti-inflammatory drug celecoxib has long been used for reducing pain, in
spite of moderate gastrointestinal side effects. In previous studies, it has been shown that …

Administration of formalin in rat paws results in stimulation of nociceptive pathways, which
leads to an increase in the excitability of neurons present in dorsal horn. This increased …

Background Celecoxib exerted analgesic effects (hypoalgesia) reversed by opioid receptor
antagonists in a model of inflammatory pain. To analyze this celecoxib-induced hypoalgesia …

Background: The analgesic effects of celecoxib, a cyclooxygenase‐2 (COX‐2) inhibitor, on
formalin‐induced pain are still controversial. The purpose of this study was to examine the …

The peripheral antinociceptive effect of the selective COX-2 inhibitor celecoxib in the
formalin-induced inflammatory pain was compared with that of resveratrol (COX-1 inhibitor) …

Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits
cyclooxygenase-2 (COX-2). Like most NSAIDs, celecoxib exhibits analgesic effects in …

In a model of peripherally induced inflammatory pain in rats, selective inhibitors of
cyclooxygenase (COX)-2 raised nociceptive thresholds above basal values, an effect …

Celecoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) and blocks prostaglandin
(PG) biosynthesis associated with inflammatory conditions. In a model of peripherally …

Background In the present study we determined the antihyperalgesic and antiallodynic effect
of celecoxib in diabetic rats as well as the possible participation of opioid receptors in the …

Non-steroidal antiinflammatory drugs (NSAIDs) are known to induce analgesia mainly via
inhibition of cyclooxygenase (COX). Although the inhibition of COX in the periphery is …