p53 Mutations in Lung Cancer Associated with Residential Radon Exposure

A Yngveson, C Williams, A Hjerpe, J Lundeberg… - … Biomarkers & Prevention, 1999 - AACR
Unusual mutation patterns in lung tumors among underground miners have been indicated,
suggesting radon-specific alterations in the genome, but the data are not consistent. To …

[HTML][HTML] Analysis of the relationship between p53 immunohistochemical expression and risk factors for lung cancer, with special emphasis on residential radon …

A Ruano-Ravina, R Pérez-Becerra, M Fraga… - Annals of oncology, 2008 - Elsevier
Background Indoor radon exposure has been postulated as the second risk factor of lung
cancer after tobacco. The objective of this work is to analyze if there exists any effect on p53 …

Analysis of radon-associated squamous cell carcinomas of the lung for a p53 gene hotspot mutation

Q Yang, H Wesch, KM Mueller, H Bartsch… - British journal of …, 2000 - nature.com
Squamous cell lung carcinomas (SCC) from former employees of the Wismut uranium
mining company (Saxony, Germany) were obtained from the Stollberg Archive in order to …

Lung cancer and residential radon in never-smokers: A pooling study in the Northwest of Spain

M Lorenzo-González, A Ruano-Ravina… - Environmental …, 2019 - Elsevier
Background Using a pooled case-control study design, including only never-smokers, we
have assessed the association of residential radon exposure with the subsequent …

Residential radon and lung cancer characteristics in never smokers

M Torres-Duran, A Ruano-Ravina… - … journal of radiation …, 2015 - Taylor & Francis
Purpose: The aim of this study is to assess if there is a relationship between residential
radon and lung cancer histological types and patients' age at diagnosis. Materials and …

Is there a specific mutation of p53 gene due to radon exposure? A systematic review

A Ruano-Ravina, MJ Faraldo-Vallés… - International journal of …, 2009 - Taylor & Francis
Purpose: To review the existing literature analysing the influence of radon exposure on
mutations in tumour protein 53 gene (TP53) in lung cancer patients. Material and methods …

Residential radon and lung cancer in never smokers. A systematic review

M Torres-Durán, JM Barros-Dios, A Fernández-Villar… - Cancer letters, 2014 - Elsevier
Radon exposure is considered the second cause of lung cancer and the first in never
smokers. We aim to assess the effect of residential radon exposure on the risk of lung cancer …

Residential radon exposure, histologic types, and lung cancer risk. A case–control study in Galicia, Spain

JM Barros-Dios, A Ruano-Ravina, M Perez-Rios… - … , biomarkers & prevention, 2012 - AACR
Background: Lung cancer is an important public health problem, and tobacco is the main
risk factor followed by residential radon exposure. Recommended exposure levels have …

Mutations of p53 and ras genes in radon-associated lung cancer from uranium miners

KH Vahakangas, RA Metcalf, JA Welsh, WP Bennett… - The Lancet, 1992 - Elsevier
Radon increases the risk of lung cancer in smoking and non-smoking underground miners.
To investigate the mutational spectrum associated with exposure to high levels of radon, we …

Lung cancer in never-smokers: a case–control study in a radon-prone area (Galicia, Spain)

M Torres-Durán, A Ruano-Ravina… - European …, 2014 - Eur Respiratory Soc
The aim of the study was to assess the effect of residential radon exposure on the risk of
lung cancer in never-smokers and to ascertain if environmental tobacco smoke modifies the …