Ginkgolide B protects neurons from ischemic injury by inhibiting the expression of RTP801
X Wu, J Su, L Chen, B Ma, X Gu, L Zhu - Cellular and molecular …, 2015 - Springer
RTP801 (also known as REDD1), a stress-related protein, is induced by several
environmental stresses such as ischemia and cigarette smoke. Although ischemia can …
environmental stresses such as ischemia and cigarette smoke. Although ischemia can …
Exposure-response analysis and mechanism of ginkgolide B's neuroprotective effect in acute cerebral ischemia/reperfusion stage in rat
D Cai, Z Luo, J Su, H Gan, Z Wang, X Liu… - Biological and …, 2022 - jstage.jst.go.jp
Ginkgolide B (GKB) is a well-established neuroprotectant for acute ischemia stroke.
However, its cerebral exposure and real-time response remain elusive in acute …
However, its cerebral exposure and real-time response remain elusive in acute …
Inhibition of NF-κB activation is associated with anti-inflammatory and anti-apoptotic effects of Ginkgolide B in a mouse model of cerebral ischemia/reperfusion injury
Ginkgolide B (GB) has potent neuroprotective effects against ischemia-induced brain injury
in vivo and in vitro. However, the underlying mechanisms of GB's neuroprotection remain …
in vivo and in vitro. However, the underlying mechanisms of GB's neuroprotection remain …
Neuroprotective effect of ginkgolide K on glutamate-induced cytotoxicity in PC 12 cells via inhibition of ROS generation and Ca2+ influx
S Ma, H Liu, H Jiao, L Wang, L Chen, J Liang, M Zhao… - Neurotoxicology, 2012 - Elsevier
Glutamate is considered to be responsible for the pathogenesis of cerebral ischemia
disease.[Ca2+] i influx and reactive oxygen species (ROS) production are considered to be …
disease.[Ca2+] i influx and reactive oxygen species (ROS) production are considered to be …
Neuroprotective effect of ginkgetin in experimental cerebral ischemia/reperfusion via apoptosis inhibition and PI3K/Akt/mTOR signaling pathway activation
Z Tian, C Tang, Z Wang - Journal of cellular biochemistry, 2019 - Wiley Online Library
Abstract Background Ginkgetin, extracted from Ginkgo biloba L leaves, has been
demonstrated to have potential anti‐inflammatory and immune‐suppressive properties. But …
demonstrated to have potential anti‐inflammatory and immune‐suppressive properties. But …
[HTML][HTML] Ginkgolide b protects against ischemic stroke via targeting ampk/pink1
Y Cao, L Yang, H Cheng - Frontiers in Pharmacology, 2022 - frontiersin.org
Introduction: Ginkgolide B (GB), which is an active constituent derived from Ginkgo biloba
leaves, has been reported to ameliorate Alzheimer's disease (AD), ischemic stroke, as well …
leaves, has been reported to ameliorate Alzheimer's disease (AD), ischemic stroke, as well …
Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling
W Zhang, J Song, R Yan, L Li, Z Xiao, W Zhou… - Acta Pharmacologica …, 2018 - nature.com
Diterpene ginkgolides meglumine injection (DGMI) is a therapeutic extract of Ginkgo biloba
L, which has been used for the treatment of cerebral ischemic stroke in China. Ginkgolides …
L, which has been used for the treatment of cerebral ischemic stroke in China. Ginkgolides …
Ginkgetin exerts anti-inflammatory effects on cerebral ischemia/reperfusion-induced injury in a rat model via the TLR4/NF-κB signaling pathway
Q Li, T Ye, T Long, X Peng - Bioscience, biotechnology, and …, 2019 - academic.oup.com
Ginkgo biloba, a natural biflavonoid isolated from Ginkgo biloba leaves, is reported to have
strong anti-inflammatory and immunosuppressive properties. The aim of this study is to …
strong anti-inflammatory and immunosuppressive properties. The aim of this study is to …
Ginkgolide B Reduces Neuronal Cell Apoptosis in the Traumatic Rat Brain: Possible Involvement of Toll‐like Receptor 4 and Nuclear Factor Kappa B Pathway
WH Yu, XQ Dong, YY Hu, M Huang… - Phytotherapy …, 2012 - Wiley Online Library
Ginkgolide B (GB) has been demonstrated to have a variety of pharmacological actions.
Accumulating evidence indicates that GB may exert a protective effect on brain injury. The …
Accumulating evidence indicates that GB may exert a protective effect on brain injury. The …
Neuroprotective effects of Ginkgolide B in focal cerebral ischemia through selective activation of prostaglandin E2 receptor EP4 and the downstream transactivation of …
H Yang, GP Li, Q Liu, SB Zong, L Li, ZL Xu… - Phytotherapy …, 2021 - Wiley Online Library
The present study was undertaken to identify whether prostaglandin E2 receptor is the
potential receptor/binding site for Ginkgolide A, Ginkgolide B, Ginkgolide K, and Bilobalide …
potential receptor/binding site for Ginkgolide A, Ginkgolide B, Ginkgolide K, and Bilobalide …