Inflammatory biomarkers predict heart failure severity and prognosis in patients with heart failure with preserved ejection fraction: a holistic proteomic approach

C Hage, E Michaëlsson, C Linde, E Donal… - Circulation …, 2017 - Am Heart Assoc
Background—Underlying mechanisms in heart failure (HF) with preserved ejection fraction
remain unknown. We investigated cardiovascular plasma biomarkers in HF with preserved …

Proteomic evaluation of the comorbidity-inflammation paradigm in heart failure with preserved ejection fraction: results from the PROMIS-HFpEF study

S Sanders-van Wijk, J Tromp, L Beussink-Nelson… - Circulation, 2020 - Am Heart Assoc
Background: A systemic proinflammatory state has been hypothesized to mediate the
association between comorbidities and abnormal cardiac structure/function in heart failure …

Prognostication in different heart failure phenotypes: the role of circulating biomarkers

AE Berezin - Journal of Circulating Biomarkers, 2016 - journals.sagepub.com
Heart failure (HF) is multifactorial syndrome with high cardiovascular (CV) morbidity and
mortality rates associated with an increasing prevalence worldwide. Measuring plasma …

Pro‐inflammatory biomarkers in stable versus acutely decompensated heart failure with preserved ejection fraction

A Abernethy, S Raza, JL Sun, KJ Anstrom… - Journal of the …, 2018 - Am Heart Assoc
Background Underlying inflammation has been increasingly recognized in heart failure with
a preserved ejection fraction (HF p EF). In this study we tested the hypothesis that pro …

Biomarker profiles in heart failure patients with preserved and reduced ejection fraction

J Tromp, MAF Khan, IJT Klip, S Meyer… - Journal of the …, 2017 - Am Heart Assoc
Background Biomarkers may help us to unravel differences in the underlying
pathophysiology between heart failure (HF) patients with a reduced ejection fraction (HF r …

Biomarker profiles in heart failure with preserved vs. reduced ejection fraction: results from the DIAST‐CHF study

A Eidizadeh, M Schnelle, A Leha… - ESC Heart …, 2023 - Wiley Online Library
Aims Chronic heart failure (HF) is a common disease and one of the leading causes of death
worldwide. Heart failure with preserved ejection fraction (HFpEF) and with reduced ejection …

Machine learning based on biomarker profiles identifies distinct subgroups of heart failure with preserved ejection fraction

RJ Woolley, D Ceelen, W Ouwerkerk… - European journal of …, 2021 - Wiley Online Library
Aims The lack of effective therapies for patients with heart failure with preserved ejection
fraction (HFpEF) is often ascribed to the heterogeneity of patients with HFpEF. We aimed to …

Inflammatory pathways in heart failure with preserved left ventricular ejection fraction: implications for future interventions

NR Pugliese, P Pellicori, F Filidei… - Cardiovascular …, 2022 - academic.oup.com
Many patients with symptoms and signs of heart failure have a left ventricular ejection
fraction≥ 50%, termed heart failure with preserved ejection fraction (HFpEF). HFpEF is a …

[HTML][HTML] Biomarkers of inflammation in heart failure

B Bozkurt, DL Mann, A Deswal - Heart failure reviews, 2010 - Springer
Heart failure (HF) is characterized by the elaboration of a portfolio of pro-inflammatory
cytokines and inflammatory mediators that are considered to contribute to disease …

Inflammation and remodeling pathways and risk of cardiovascular events in patients with ischemic heart failure and reduced ejection fraction

N Girerd, J Cleland, SD Anker, W Byra, CSP Lam… - Scientific reports, 2022 - nature.com
Patients with heart failure (HF) and coronary artery disease (CAD) have a high risk for
cardiovascular (CV) events including HF hospitalization, stroke, myocardial infarction (MI) …