Endothelial nitric oxide synthase (eNOS) produces nitric oxide (NO) which, after diffusing
into vascular smooth muscle cells, activates guanylate cyclase leading to vasodilatation. A …

Objectives To test whether the Glu298Asp polymorphism of the endothelial nitric oxide
synthase (eNOS) gene is of functional relevance in humans by altering endothelium …

Significant association between a Glu298Asp polymorphism of the endothelial nitric oxide
synthase (eNOS) gene and essential hypertension was recently reported in Japanese …

Although the pathogenic mechanisms involved in predisposing individuals to hypertension
are not well defined, evidence is accumulating that suggests a strong genetic transmission …

Objective The Glu298Asp (E/D) polymorphism of the endothelial nitric oxide synthase
(eNOS) gene has been related to hypertension. Since several studies have produced …

The G894T endothelial nitric oxide synthase (eNOS) polymorphism results in a Glu to Asp
substitution at position 298. This position is located externally on the protein and as the …

The human endothelial nitric oxide synthase (eNOS) gene is highly polymorphic. Evidence
for the involvement of eNOS single nucleotide polymorphisms in the development of …

Nitric oxide (NO), produced by endothelial nitric oxide synthase (eNOS), plays important
roles in normal vascular homeostasis, and reduced endothelial NO bioactivity is an …

Objective—To assess the role of the endothelial nitric oxide synthase (eNOS) gene variant
as a risk factor for atherosclerosis we sought to investigate whether the Glu298Asp …

The Glu298Asp polymorphism of human endothelial nitric oxide synthase (eNOS) has been
reported to be associated with several cardiovascular diseases, including hypertension and …