Genome‐wide profiling of oral squamous cell carcinoma

YJ Chen, SC Lin, T Kao, CS Chang… - The Journal of …, 2004 - Wiley Online Library
Oral squamous cell carcinoma (OSCC) is a common malignancy, the incidence of which is
particularly high in some Asian countries due to the geographically linked areca quid (AQ) …

[HTML][HTML] Exome sequencing of oral squamous cell carcinoma reveals molecular subgroups and novel therapeutic opportunities

SC Su, CW Lin, YF Liu, WL Fan, MK Chen, CP Yu… - Theranostics, 2017 - ncbi.nlm.nih.gov
Oral squamous cell carcinoma (OSCC), an epithelial malignancy affecting a variety of
subsites in the oral cavity, is prevalent in Asia. The survival rate of OSCC patients has not …

Array‐comparative genomic hybridization to detect genomewide changes in microdissected primary and metastatic oral squamous cell carcinomas

CJ Liu, SC Lin, YJ Chen, KM Chang… - … in cooperation with …, 2006 - Wiley Online Library
Oral squamous cell carcinoma (OSCC) is a common worldwide malignancy. However, it is
unclear what, if any, genomic alterations occur as the disease progresses to invasive and …

A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma

CH Peng, CT Liao, SC Peng, YJ Chen, AJ Cheng… - PloS one, 2011 - journals.plos.org
Molecular methods for predicting prognosis in patients with oral cavity squamous cell
carcinoma (OSCC) are urgently needed, considering its high recurrence rate and tendency …

Genome wide profiling in oral squamous cell carcinoma identifies a four genetic marker signature of prognostic significance

VK Vincent-Chong, I Salahshourifar, KM Woo, A Anwar… - PloS one, 2017 - journals.plos.org
Background Cancers of the oral cavity are primarily oral squamous cell carcinomas
(OSCCs). Many of the OSCCs present at late stages with an exceptionally poor prognosis. A …

Copy number amplification of 3q26–27 oncogenes in microdissected oral squamous cell carcinoma and oral brushed samples from areca chewers

SC Lin, CJ Liu, SY Ko, HC Chang… - The Journal of …, 2005 - Wiley Online Library
Oral squamous cell carcinoma (OSCC) is a worldwide disease. In South Asians, the high
prevalence of OSCC is tightly linked to areca chewing. The prognosis for OSCC remains …

Genome‐wide analysis of oral squamous cell carcinomas revealed over expression of ISG15, Nestin and WNT11

VK Vincent‐Chong, SM Ismail, ZAA Rahman… - Oral …, 2012 - Wiley Online Library
Oral Diseases (2012) 18, 469–476 Background: Multistep pathways and mechanisms are
involved in the development of oral cancer. Chromosomal alterations are one of such key …

The role of components of the extracellular matrix and inflammation on oral squamous cell carcinoma metastasis

T Tanis, ZB Cincin, B Gokcen-Rohlig, ES Bireller… - Archives of oral …, 2014 - Elsevier
Objectives Oral squamous cell carcinoma (OSCC) accounts for about 90% of malignant oral
lesions, and is identified as the most frequently occurring malignant tumour of oral …

Comparative genomic hybridization reveals genetic progression of oral squamous cell carcinoma from dysplasia via two different tumourigenic pathways

Y Noutomi, A Oga, K Uchida, M Okafuji… - The Journal of …, 2006 - Wiley Online Library
To clarify the genetic pathway (s) involved in the development and progression of oral
squamous cell carcinoma (OSCC), as well as the relationship between genetic aberrations …

[HTML][HTML] Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies

MZH Fadlullah, IKN Chiang, KR Dionne, P San Yee… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Emerging biological and translational insights from large sequencing efforts underscore the
need for genetically-relevant cell lines to study the relationships between genomic …