[HTML][HTML] Interactions between LAMP3+ dendritic cells and T-cell subpopulations promote immune evasion in papillary thyroid carcinoma

Z Wang, X Ji, Y Zhang, F Yang, H Su… - … for Immunotherapy of …, 2024 - ncbi.nlm.nih.gov
Background The incidence of papillary thyroid cancer (PTC) continues to rise all over the
world, 10–15% of the patients have a poor prognosis. Although immunotherapy has been …

Single-cell RNA sequencing reveals a novel cell type and immunotherapeutic targets in papillary thyroid cancer

Z Wang, Y Rixiati, W Jiang, C Ye, C Huang, C Tang… - medRxiv, 2021 - medrxiv.org
Papillary thyroid cancer (PTC) is the most common thyroid malignancy. Although PTC
usually has a favorable prognosis, some aggressive PTC subtypes and lymph node (LN) …

[HTML][HTML] Single-cell transcriptome analysis reveals inter-tumor heterogeneity in bilateral papillary thyroid carcinoma

T Wang, J Shi, L Li, X Zhou, H Zhang, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The tumor microenvironment (TME) plays a pivotal role in cancer progression in
papillary thyroid carcinoma (PTC), yet the composition and the phenotype of cells within the …

Papillary thyroid carcinoma behavior: clues in the tumor microenvironment

K Bergdorf, DC Ferguson, M Mehrad… - Endocrine-Related …, 2019 - erc.bioscientifica.com
The prevalence of thyroid carcinoma is increasing and represents the most common
endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most frequent …

[HTML][HTML] Pathomics and single-cell analysis of papillary thyroid carcinoma reveal the pro-metastatic influence of cancer-associated fibroblasts

Y Wang, X Li, Q Gang, Y Huang, M Liu, H Zhang… - BMC cancer, 2024 - Springer
Background Papillary thyroid carcinoma (PTC) is globally prevalent and associated with an
increased risk of lymph node metastasis (LNM). The role of cancer-associated fibroblasts …

[HTML][HTML] Single‐cell transcriptomic landscape reveals the differences in cell differentiation and immune microenvironment of papillary thyroid carcinoma between …

M Peng, G Wei, Y Zhang, H Li, Y Lai, Y Guo, Y Chen… - Cell & bioscience, 2021 - Springer
Background Papillary thyroid carcinoma (PTC) is the main pathological type of thyroid
carcinoma (TC). Gender is a prominent background parameter for patients with PTC. Here …

[HTML][HTML] Immune cell confrontation in the papillary thyroid carcinoma microenvironment

Z Xie, X Li, Y He, S Wu, S Wang, J Sun, Y He… - Frontiers in …, 2020 - frontiersin.org
Background Papillary thyroid cancer has been associated with chronic inflammation. A
systematic understanding of immune cell infiltration in PTC is essential for subsequent …

[HTML][HTML] Role of cytotoxic T cells and PD-1 immune checkpoint pathway in papillary thyroid carcinoma

S Banerjee, U Nahar, D Dahiya, S Mukherjee… - Frontiers in …, 2022 - frontiersin.org
Background Lymphocytic thyroiditis (LT) is frequently seen in the tumor microenvironment
(TME) of papillary thyroid carcinomas (PTCs). However, the characteristic of these tumor …

[HTML][HTML] Tumor-infiltrating immune cell landscapes in the lymph node metastasis of papillary thyroid cancer

M Amanullah, M Pan, K Lu, X Pan, Y Lu, D Luo, P Liu - Current Oncology, 2023 - mdpi.com
Regional lymph node metastasis (LNM) increases the risk of distant metastasis in papillary
thyroid cancer (PTC) patients. However, it remains unclear how tumor cells in PTC patients …

[HTML][HTML] Immune profiling identifies CD8+ T-cell subset signatures as prognostic markers for recurrence in papillary thyroid cancer

Z Chen, ML Guo, YY Li, K Yan, L Li, F Shen… - Frontiers in …, 2022 - frontiersin.org
Background Thyroid tissue has a special immune microenvironment that is not well
characterized. Whether immune cells have a prognostic value in the recurrence of papillary …