CD47 is a “don't eat me” signal to phagocytes, that is overexpressed in solid and blood
tumors and represents a key mechanism of immune evasion in cancer. 1 Engagement of …

The pericentric inversion of chromosome 16 (inv (16)(p12q22)) is a characteristic karyotypic
abnormality associated with acute myeloid leukemia, most commonly of the M4Eo subtype. It …

Background: Immunophenotyping improves both accuracy and reproducibility of acute
leukemia classification and is considered particularly useful for identifying aberrant lineage …

Detection of minimal/measurable residual disease (MRD) in acute myeloid leukemia (AML)
is important for guiding patient‐specific clinical management. Natural killer (NK) cells can …

Inv (16)(p13; q22) or t (16; 16)(p13; q22) is one of the most frequent recurring chromosomal
rearrangements detected in AML, generally observed in cases showing myelo-monocytic …

Acute myelomonocytic leukemia with marrow eosinophilia (M4Eo) is strongly associated
with inv (16)(p13q22)[1], del (16)(q22)[2], or t (16; 16)(p13; q22)[31. However, there are …

Context.—Immunophenotyping of bone marrow (BM) specimens with acute myelogenous
leukemia (AML) may be performed by flow cytometric (FC) or immunohistochemical (IH) …

An increasing number of acute leukemias coexpressed markers normally believed to be
restricted to a single lineage have been found recently. This special subgroup of leukemias …

BACKGROUND: The expression of CD56 is considered a bad prognostic factor for overall
survival, lower rates or short complete remission and extramedullary invasion but the results …

While assessing the prognostic implications of immunophenotyping in 382 patients enrolled
in treatment protocols of the Eastern Cooperative Oncology Group (ECOG) for de novo adult …