Antimicrobial/anticancer peptides: Bioactive molecules and therapeutic agents

K Kardani, A Bolhassani - Immunotherapy, 2021 - Taylor & Francis
Antimicrobial peptides (AMPs) have been known as host-defense peptides. These cationic
and amphipathic peptides are relatively short (∼ 5–50 L-amino acids) with molecular weight …

Antimicrobial peptides with anticancer activity: Today status, trends and their computational design

M Kordi, Z Borzouyi, S Chitsaz, M hadi Asmaei… - Archives of biochemistry …, 2023 - Elsevier
Some antimicrobial peptides have been shown to be able to inhibit the proliferation of
cancer cell lines. Various strategies for treating cancers with active peptides have been …

From antimicrobial to anticancer peptides. A review

D Gaspar, AS Veiga, MARB Castanho - Frontiers in microbiology, 2013 - frontiersin.org
Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many
organisms. Although AMPs have been essentially studied and developed as potential …

ACPred: a computational tool for the prediction and analysis of anticancer peptides

N Schaduangrat, C Nantasenamat, V Prachayasittikul… - Molecules, 2019 - mdpi.com
Anticancer peptides (ACPs) have emerged as a new class of therapeutic agent for cancer
treatment due to their lower toxicity as well as greater efficacy, selectivity and specificity …

Discovery, optimization, and clinical application of natural antimicrobial peptides

AA Rodríguez, A Otero-González, M Ghattas… - Biomedicines, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are widespread in multicellular organisms. These structurally
diverse molecules are produced as the first line of defense against pathogens such as …

Antimicrobial peptides (AMPs): roles, functions and mechanism of action

R Seyfi, FA Kahaki, T Ebrahimi… - International Journal of …, 2020 - Springer
Antimicrobial peptides (AMPs) are a crucial part of innate immunity that exist in the most of
living organisms. In fact, AMPs have ability to incite the innate immune response and combat …

Antimicrobial peptides against colorectal cancer-a focused review

S Chauhan, DK Dhawan, A Saini, S Preet - Pharmacological Research, 2021 - Elsevier
Despite recent advances in the treatment of colorectal cancer (CRC), low patient survival
rate due to emergence of drug resistant cancer cells, metastasis and multiple deleterious …

Biomedical relevance of novel anticancer peptides in the sensitive treatment of cancer

OO Bakare, A Gokul, R Wu, LA Niekerk, A Klein… - Biomolecules, 2021 - mdpi.com
The global increase in cancer mortality and economic losses necessitates the cautious
quest for therapeutic agents with compensatory advantages over conventional therapies …

Discovering new in silico tools for antimicrobial peptide prediction

M Torrent, M Victoria Nogues, E Boix - Current drug targets, 2012 - ingentaconnect.com
Antimicrobial peptides (AMPs) are important effectors of the innate immune system and play
a vital role in the prevention of infections. Due to the increased emergence of new antibiotic …

Clinical applications and anticancer effects of antimicrobial peptides: from bench to bedside

A Jafari, A Babajani, R Sarrami Forooshani… - Frontiers in …, 2022 - frontiersin.org
Cancer is a multifaceted global health issue and one of the leading causes of death
worldwide. In recent years, medical science has achieved great advances in the diagnosis …