Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

M Chehelgerdi, M Chehelgerdi, OQB Allela… - Molecular cancer, 2023 - Springer
The use of nanotechnology has the potential to revolutionize the detection and treatment of
cancer. Developments in protein engineering and materials science have led to the …

Nanomedicine tumor targeting

T Lammers - Advanced Materials, 2024 - Wiley Online Library
Nanomedicines are extensively explored for cancer therapy. By delivering drug molecules
more efficiently to pathological sites and by attenuating their accumulation in healthy organs …

Nano-based approved pharmaceuticals for cancer treatment: present and future challenges

F Rodríguez, P Caruana, N De la Fuente, P Español… - Biomolecules, 2022 - mdpi.com
Cancer is one of the main causes of death worldwide. To date, and despite the advances in
conventional treatment options, therapy in cancer is still far from optimal due to the non …

Perspectives on the past, present, and future of cancer nanomedicine

YS Youn, YH Bae - Advanced drug delivery reviews, 2018 - Elsevier
The justification of cancer nanomedicine relies on enhanced permeation (EP) and retention
(R) effect and the capability of intracellular targeting due primarily to size after internalization …

Recent insights in nanotechnology-based drugs and formulations designed for effective anti-cancer therapy

E Piktel, K Niemirowicz, M Wątek, T Wollny… - Journal of …, 2016 - Springer
The rapid development of nanotechnology provides alternative approaches to overcome
several limitations of conventional anti-cancer therapy. Drug targeting using functionalized …

Targeted therapy using nanotechnology: focus on cancer

V Sanna, N Pala, M Sechi - International journal of nanomedicine, 2014 - Taylor & Francis
Recent advances in nanotechnology and biotechnology have contributed to the
development of engineered nanoscale materials as innovative prototypes to be used for …

Best practices in cancer nanotechnology: perspective from NCI nanotechnology alliance

WC Zamboni, V Torchilin, AK Patri, J Hrkach… - Clinical cancer …, 2012 - AACR
Historically, treatment of patients with cancer using chemotherapeutic agents has been
associated with debilitating and systemic toxicities, poor bioavailability, and unfavorable …

Nanomedicine in cancer therapy

D Fan, Y Cao, M Cao, Y Wang, Y Cao… - Signal Transduction and …, 2023 - nature.com
Cancer remains a highly lethal disease in the world. Currently, either conventional cancer
therapies or modern immunotherapies are non-tumor-targeted therapeutic approaches that …

Nanotechnology toward treating cancer: A comprehensive review

G Pillai - Applications of targeted nano drugs and delivery …, 2019 - Elsevier
Nanomedicine, the application of nanotechnology to treatment and prevention of diseases,
is an emerging form of drug therapy that utilizes nanomaterials as drug carriers for …

Cancer nanomedicine: progress, challenges and opportunities

J Shi, PW Kantoff, R Wooster, OC Farokhzad - Nature reviews cancer, 2017 - nature.com
The intrinsic limits of conventional cancer therapies prompted the development and
application of various nanotechnologies for more effective and safer cancer treatment …