[HTML][HTML] Prolonged beneficial effect of brief erythropoietin peptide JM4 therapy on chronic relapsing EAE
D Gaindh, YB Choi, M Marchese, P Dowling, S Cook… - …, 2021 - Elsevier
Potent beneficial immunomodulatory and anti-inflammatory effects of whole-molecule
erythropoietin have been demonstrated in a variety of animal disease models including …
erythropoietin have been demonstrated in a variety of animal disease models including …
Csf1R inhibition attenuates experimental autoimmune encephalomyelitis and promotes recovery
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system
(CNS) characterized by progressive neuronal demyelination and degeneration. Much of this …
(CNS) characterized by progressive neuronal demyelination and degeneration. Much of this …
A novel combination approach to effectively reduce inflammation and neurodegeneration in multiple sclerosis models
A Haque, NNM Trager, JT Butler, A Das… - Neurochemistry …, 2024 - Elsevier
Multiple sclerosis (MS) is an autoimmune disease characterized by immune-mediated
attacks on the central nervous system (CNS), resulting in demyelination and recurring T-cell …
attacks on the central nervous system (CNS), resulting in demyelination and recurring T-cell …
B Lymphocytes from MS Patients Induce CNS Pathology in a Murine Brain Slice Model (P5. 321)
Objective: Discover mechanisms by which B cells may drive MS pathogenesis. Background:
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system …
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system …
Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis
C Criscuolo, A Cianflone, R Lanzillo, D Carrella… - Scientific Reports, 2019 - nature.com
To investigate the effects of Glatiramer Acetate (GA) on B cells by an integrated
computational and experimental approach. GA is an immunomodulatory drug approved for …
computational and experimental approach. GA is an immunomodulatory drug approved for …
Macrophage brain infiltration in experimental autoimmune encephalomyelitis is not completely compromised by suppressed T-cell invasion: in vivo magnetic …
MSA Deloire, T Touil, B Brochet… - Multiple Sclerosis …, 2004 - journals.sagepub.com
Large inflammatory infiltrates of T cells, macrophages and B cells in the central nervous
system (CNS) contribute to the pathogenesis of multiple sclerosis (MS). The passage of T …
system (CNS) contribute to the pathogenesis of multiple sclerosis (MS). The passage of T …
Disturbed presynaptic Ca2+ signaling in photoreceptors in the EAE mouse model of multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease caused by an auto-reactive immune
system. Recent studies also demonstrated synapse dysfunctions in MS patients and MS …
system. Recent studies also demonstrated synapse dysfunctions in MS patients and MS …
Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis
D Morsali, D Bechtold, W Lee, S Chauhdry… - Brain, 2013 - academic.oup.com
Axonal degeneration is a major cause of permanent disability in the inflammatory
demyelinating disease multiple sclerosis, but no therapies are known to be effective in …
demyelinating disease multiple sclerosis, but no therapies are known to be effective in …
Therapeutic depletion of monocyte-derived cells protects from long-term axonal loss in experimental autoimmune encephalomyelitis
MA Moreno, T Burns, P Yao, L Miers, D Pleasure… - Journal of …, 2016 - Elsevier
Studies in multiple sclerosis and its animal model experimental autoimmune
encephalomyelitis (EAE) suggest that peripheral monocyte-derived cells (MDCs) are …
encephalomyelitis (EAE) suggest that peripheral monocyte-derived cells (MDCs) are …
Promoting remyelination through cell transplantation therapies in a model of viral‐induced neurodegenerative disease
V Mangale, LL McIntyre, CM Walsh… - Developmental …, 2019 - Wiley Online Library
Multiple sclerosis (MS) is a central nervous system (CNS) disease characterized by chronic
neuroinflammation, demyelination, and axonal damage. Infiltration of activated lymphocytes …
neuroinflammation, demyelination, and axonal damage. Infiltration of activated lymphocytes …