Thymoquinone Induced Leishmanicidal Effect via Programmed Cell Death in Leishmania donovani
Visceral leishmaniasis (VL) or kala-azar is a vector-borne dreaded protozoal infection that is
caused by the parasite Leishmania donovani. With increases in the dramatic infection rates …
caused by the parasite Leishmania donovani. With increases in the dramatic infection rates …
Current leishmaniasis drug discovery
AC Pinheiro, MVN de Souza - RSC Medicinal Chemistry, 2022 - pubs.rsc.org
Leishmaniasis is a complex protozoan infectious disease and, associated with malnutrition,
poor health services and unavailability of prophylactic control measures, neglected …
poor health services and unavailability of prophylactic control measures, neglected …
An adamantamine derivative as a drug candidate for the treatment of visceral leishmaniasis
S Pomel, S Cojean, V Pons, JC Cintrat… - Journal of …, 2021 - academic.oup.com
Background This study aimed to investigate compounds acting on the host cell machinery to
impair parasite installation with the possible advantage of limiting drug resistance. The …
impair parasite installation with the possible advantage of limiting drug resistance. The …
Leishmania treatment and prevention: Natural and synthesized drugs
AA Bekhit, E El-Agroudy, A Helmy, TM Ibrahim… - European journal of …, 2018 - Elsevier
Leishmaniasis affects over 150 million people all over the world, especially in subtropical
regions. Currently used antileishmanial synthesized drugs are associated with some …
regions. Currently used antileishmanial synthesized drugs are associated with some …
Improved treatment of visceral leishmaniasis (kala-azar) by using combination of ketoconazole, miltefosine with an immunomodulator—Picroliv
N Shakya, SA Sane, P Vishwakarma, P Bajpai, S Gupta - Acta tropica, 2011 - Elsevier
Visceral leishmaniasis (VL) caused by the parasite Leishmania donovani, is a potentially
fatal disease. It is characterized by prolonged fever, enlarged spleen and liver, substantial …
fatal disease. It is characterized by prolonged fever, enlarged spleen and liver, substantial …
Structure–activity relationship of (−) mammea A/BB derivatives against Leishmania amazonensis
MA Brenzan, CV Nakamura, BP Dias Filho… - Biomedicine & …, 2008 - Elsevier
To study the structure–activity relationship of coumarin (−) mammea A/BB isolated from the
CH2Cl2 extract of Calophyllum brasiliense leaves, we evaluated the antileishmanial activity …
CH2Cl2 extract of Calophyllum brasiliense leaves, we evaluated the antileishmanial activity …
[HTML][HTML] Discovery of New Chemical Tools against Leishmania amazonensis via the MMV Pathogen Box
The protozoan parasite Leishmania causes a spectrum of diseases and there are over 1
million infections each year. Current treatments are toxic, expensive, and difficult to …
million infections each year. Current treatments are toxic, expensive, and difficult to …
Evaluation of miltefosine against Leishmania major (MRHO/IR/75/ER): in vitro and in vivo studies
J Esmaeili, M Mohebali, GHH EDRISIAN, SM Rezayat… - 2008 - sid.ir
CUTANEOUS LEISHMANIASIS is endemic in 88 different countries. There are an estimated
1.5 million new cases each year, with over 90% occurring in Afghanistan, Algeria, Iran, Iraq …
1.5 million new cases each year, with over 90% occurring in Afghanistan, Algeria, Iran, Iraq …
In vivo antileishmanial activity of plant-based secondary metabolites
LFD Passero, MD Laurenti, G Santos-Gomes… - … Resistance with Herbal …, 2013 - Elsevier
Leishmaniasis is an infectious disease caused by parasites belonging to the Leishmania
genus. This disease has a prevalence that exceeds 12 million, and approximately 350 …
genus. This disease has a prevalence that exceeds 12 million, and approximately 350 …
Alkaloids: future prospective to combat leishmaniasis
Leishmaniasis, a vector-borne parasitic disease resulting from infection of macrophages by
obligate intracellular parasites of genus Leishmania, has been considered a major tropical …
obligate intracellular parasites of genus Leishmania, has been considered a major tropical …