Serology enhances molecular diagnosis of respiratory virus infections other than influenza in children and adults hospitalized with community-acquired pneumonia

Y Zhang, SK Sakthivel, A Bramley, S Jain… - Journal of clinical …, 2017 - Am Soc Microbiol
Both molecular and serological assays have been used previously to determine the etiology
of community-acquired pneumonia (CAP). However, the extent to which these methods are …

Utilization of viral molecular diagnostics among children hospitalized with community acquired pneumonia

GS Schulert, PD Hain, DJ Williams - Hospital pediatrics, 2014 - publications.aap.org
Objective: To examine whether results of a polymerase chain reaction–based respiratory
viral panel (RVP) are associated with changes in antibiotic use or differential clinical …

Respiratory viral detection in children and adults: comparing asymptomatic controls and patients with community-acquired pneumonia

WH Self, DJ Williams, Y Zhu, K Ampofo… - The Journal of …, 2016 - academic.oup.com
Background. The clinical significance of viruses detected in patients with community-
acquired pneumonia (CAP) is often unclear. Methods. We conducted a prospective study to …

Practical implementation of a multiplex PCR for acute respiratory tract infections in children

P Gruteke, AS Glas, M Dierdorp… - Journal of clinical …, 2004 - Am Soc Microbiol
Molecular testing for acute respiratory infections (ARIs) has documented value but limited
implementation due to questions that typically slow the acceptance of new tests. This study …

Serology as an adjunct to polymerase chain reaction assays for surveillance of acute respiratory virus infections

P Sawatwong, M Chittaganpitch, H Hall… - Clinical infectious …, 2012 - academic.oup.com
Diagnostic testing for viral infections has evolved during the past decade. Documenting a
seroconversion, or significant increase in antibody titer between paired acute-phase and …

Viral infection in adults hospitalized with community-acquired pneumonia: prevalence, pathogens, and presentation

J Johnstone, SR Majumdar, JD Fox, TJ Marrie - Chest, 2008 - Elsevier
Background The potential role of respiratory viruses in the natural history of community-
acquired pneumonia (CAP) in adults has not been well described since the advent of …

Editorial Commentary: What is the Real Role of Respiratory Viruses in Severe Community-Acquired Pneumonia?

O Ruuskanen, A Järvinen - Clinical infectious diseases, 2014 - academic.oup.com
The impact of respiratory virus infections (RVIs) on community-acquired pneumonia (CAP) in
adults is increasingly recognized. The role of influenza A virus in causing pneumonia has …

The clinical impact of the detection of potential etiologic pathogens of community-acquired pneumonia

G Gelfer, J Leggett, J Myers, L Wang… - … microbiology and infectious …, 2015 - Elsevier
The etiology of community-acquired pneumonia (CAP) is determined in less than half of the
patients based on cultures of sputum and blood plus testing urine for the antigens of …

The relationship between respiratory viral loads and diagnosis in children presenting to a pediatric hospital emergency department

S Utokaparch, D Marchant, JV Gosselink… - The Pediatric …, 2011 - journals.lww.com
Background: Respiratory viral infections account for a considerable proportion of pediatric
emergency room visits. Illnesses range in severity from mild upper respiratory tract infections …

Spectrum of respiratory viruses in children with community-acquired pneumonia

ML García-García, C Calvo, F Pozo… - The Pediatric …, 2012 - journals.lww.com
Background: Community-acquired pneumonia (CAP) remains a significant cause for
childhood morbidity worldwide. We designed a study with the objective of describing the …