Laboratory methods for determining pneumonia etiology in children

DR Murdoch, KL O'Brien, AJ Driscoll… - Clinical infectious …, 2012 - academic.oup.com
Laboratory diagnostics are a core component of any pneumonia etiology study. Recent
advances in diagnostic technology have introduced newer methods that have greatly …

Standardization of laboratory methods for the PERCH study

AJ Driscoll, RA Karron, SC Morpeth… - Clinical Infectious …, 2017 - academic.oup.com
Abstract The Pneumonia Etiology Research for Child Health study was conducted across 7
diverse research sites and relied on standardized clinical and laboratory methods for the …

Use and evaluation of molecular diagnostics for pneumonia etiology studies

N Bhat, KL O'Brien, RA Karron… - Clinical infectious …, 2012 - academic.oup.com
Comprehensive microbiological testing will be a core function of the Pneumonia Etiology
Research for Child Health (PERCH) project. The development stage of PERCH provided the …

Addressing the analytic challenges of cross-sectional pediatric pneumonia etiology data

LL Hammitt, DR Feikin, JAG Scott… - Clinical infectious …, 2017 - academic.oup.com
Despite tremendous advances in diagnostic laboratory technology, identifying the pathogen
(s) causing pneumonia remains challenging because the infected lung tissue cannot usually …

The enduring challenge of determining pneumonia etiology in children: considerations for future research priorities

DR Feikin, LL Hammitt, DR Murdoch… - Clinical infectious …, 2017 - academic.oup.com
Pneumonia kills more children each year worldwide than any other disease. Nonetheless,
accurately determining the causes of childhood pneumonia has remained elusive. Over the …

Specimen collection for the diagnosis of pediatric pneumonia

LL Hammitt, DR Murdoch, JAG Scott… - Clinical infectious …, 2012 - academic.oup.com
Diagnosing the etiologic agent of pneumonia has an essential role in ensuring the most
appropriate and effective therapy for individual patients and is critical to guiding the …

A literature review and survey of childhood pneumonia etiology studies: 2000–2010

Z Gilani, YD Kwong, OS Levine… - Clinical infectious …, 2012 - academic.oup.com
Abstract The Pneumonia Etiology Research for Child Health (PERCH) project is the largest
multicountry etiology study of childhood pneumonia since the Board on Science and …

Standardization of clinical assessment and sample collection across all PERCH study sites

J Crawley, C Prosperi, HC Baggett… - Clinical infectious …, 2017 - academic.oup.com
Background. Variable adherence to standardized case definitions, clinical procedures,
specimen collection techniques, and laboratory methods has complicated the interpretation …

The Pneumonia Etiology Research for Child Health Project: a 21st century childhood pneumonia etiology study

OS Levine, KL O'Brien, M Deloria-Knoll… - Clinical infectious …, 2012 - academic.oup.com
Abstract The Pneumonia Etiology Research for Child Health (PERCH) project is a 7-country,
standardized, comprehensive evaluation of the etiologic agents causing severe pneumonia …

Limited utility of polymerase chain reaction in induced sputum specimens for determining the causes of childhood pneumonia in resource-poor settings: findings from …

DM Thea, P Seidenberg, DE Park… - Clinical Infectious …, 2017 - academic.oup.com
Background. Sputum examination can be useful in diagnosing the cause of pneumonia in
adults but is less well established in children. We sought to assess the diagnostic utility of …