Approximately 1,000 species of the fungal phyla Microsporidia, Chytridiomycota,
Entomophthoromycota (order: Entomophthorales), Basidiomycota, and Ascomycota are …

Secondary metabolites are well known for their ability to impede other microorganisms.
Reanalysis of a screen of natural products using the Caenorhabditis elegans-Candida …

Antibiotic resistance is becoming a burning issue due to the frequent use of antibiotics for
curing common bacterial infections, indicating that we are running out of effective antibiotics …

Highlights•Numerous species throughout Hypocreales are used for the biological control of
plant diseases and pests.•Genome data is available for many species to understand …

Exploration of natural sources for novel bioactive compounds has been an emerging field of
medicine over the past decades, providing drugs or lead compounds of considerable …

Indole-diterpenes (IDTs) such as the aflatrems, janthitrems, lolitrems, paspalitrems,
penitrems, shearinines, sulpinines, and terpendoles are biogenetically related but …

World population growth and modernization have engendered multiple environmental
problems: the propagation of humans and crop diseases and the development of multi-drug …

Natural product search is undergoing resurgence upon the discovery of a huge previously
unknown potential for secondary metabolite (SM) production hidden in microbial genomes …

Endophytic fungi are a rich source of secondary metabolites. The interactions between
endophytes and their hosts lead to the production of several bioactive substances grouped …

A major problem in the discovery of new biologically active compounds from natural
products is the reisolation of known compounds. Such reisolations waste time and …