Inhibitory effects of flavonoids extracted from Nepalese propolis on the LPS signaling pathway

M Funakoshi-Tago, K Ohsawa, T Ishikawa… - International …, 2016 - Elsevier
Flavonoids, particularly those derived from plants, harbor biological effects such as anti-
inflammation and the inhibition of cancer progression. In the present study, we investigated …

Anti-inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway

M Funakoshi-Tago, K Okamoto, R Izumi, K Tago… - International …, 2015 - Elsevier
Propolis has been used in folk medicine to improve health and prevent inflammatory
diseases; however, the components that exhibit its anti-inflammatory activity remain …

(E)-1-(4-ethoxyphenyl)-3-(4-nitrophenyl)-prop-2-en-1-one suppresses LPS-induced inflammatory response through inhibition of NF-κB signaling pathway

J Xu, YY Jia, SR Chen, JT Ye, XZ Bu, Y Hu… - International …, 2013 - Elsevier
Flavonoids are a class of compounds that exist in nature with the structure of 2-phenyl-
chromone. In Chinese traditional medicine, herbal drugs containing flavonoids are widely …

Molecular Mechanisms Underlying the In Vitro Anti‐Inflammatory Effects of a Flavonoid‐Rich Ethanol Extract from Chinese Propolis (Poplar Type)

K Wang, S Ping, S Huang, L Hu, H Xuan… - Evidence‐Based …, 2013 - Wiley Online Library
China produces the greatest amount of propolis but there is still lack of basic studies on its
pharmacological mechanisms. Our previous study found that ethanol extract from Chinese …

Glossogyne tenuifolia acts to inhibit inflammatory mediator production in a macrophage cell line by downregulating LPS-induced NF-κB

MJ Wu, L Wang, HY Ding, CY Weng, JH Yen - Journal of Biomedical …, 2004 - Springer
Abstract Glossogyne tenuifolia (hsiang-ju)(GT) is a traditional antipyretic herb used in
Chinese medicine; however, no information is available to explain its action. The objective of …

[HTML][HTML] Polyphenol-rich propolis extracts from China and Brazil exert anti-inflammatory effects by modulating ubiquitination of TRAF6 during the activation of NF-κB

K Wang, L Hu, XL Jin, QX Ma, MC Marcucci… - Journal of Functional …, 2015 - Elsevier
Propolis has documented anti-inflammatory properties, although its mechanisms of action
are poorly understood. In this study, the anti-inflammatory effects of polyphenol-rich propolis …

Anti-Inflammatory Effects, SAR, and Action Mechanism of Monoterpenoids from Radix Paeoniae Alba on LPS-Stimulated RAW 264.7 Cells

X Bi, L Han, T Qu, Y Mu, P Guan, X Qu, Z Wang… - Molecules, 2017 - mdpi.com
Nine monoterpenoids from Radix Paeoniae Alba, including paeoniflorin derivatives,
paeoniflorin (PF), 4-O-methylpaeoniflorin (MPF), 4-O-methylbenzoylpaeoniflorin (MBPF); …

Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-κB and MAPK activation in macrophages

MC Búfalo, I Ferreira, G Costa, V Francisco… - Journal of …, 2013 - Elsevier
Ethnopharmacological relevance Propolis is a bee product with numerous biological and
pharmacological properties, such as immunomodulatory and anti-inflammatory activities. It …

Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-κB activation

YC Chen, LL Yang, TJF Lee - Biochemical pharmacology, 2000 - Elsevier
Polyphenols are major components of many traditional herbal remedies, which exhibit
several beneficial effects including anti-inflammation. The exact mechanism of the anti …

Quaternary alkaloid, pseudocoptisine isolated from tubers of Corydalis turtschaninovi inhibits LPS-induced nitric oxide, PGE2, and pro-inflammatory cytokines …

KJ Yun, JS Shin, JH Choi, NI Back, HG Chung… - International …, 2009 - Elsevier
It is well known that pro-inflammatory mediators like nitric oxide (NO), prostaglandin E2
(PGE2), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) contribute to the courses of …