[HTML][HTML] Genetic associations in diabetic nephropathy: a meta-analysis

AL Mooyaart, EJJ Valk, LA Van Es, JA Bruijn… - Diabetologia, 2011 - Springer
Aims/hypothesis This meta-analysis assessed the pooled effect of each genetic variant
reproducibly associated with diabetic nephropathy. Methods PubMed, EMBASE and Web of …

Replication study for the association of 3 SNP loci identified in a genome-wide association study for diabetic nephropathy in European type 1 diabetes with diabetic …

S Maeda, M Imamura, M Kurashige, S Araki… - Clinical and …, 2013 - Springer
Background A recent genome-wide association study for diabetic nephropathy in European
type 1 diabetes identified 3 candidate loci for diabetic nephropathy. In this study, we …

Genetics of cardiovascular and renal complications in diabetes

RCW Ma - Journal of Diabetes Investigation, 2016 - Wiley Online Library
The development of debilitating complications represents a major heathcare burden
associated with the treatment of diabetes. Despite advances in new therapies for controlling …

[HTML][HTML] Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome …

G Paré, DI Chasman, AN Parker, DM Nathan… - PLoS …, 2008 - journals.plos.org
Type 2 diabetes is a leading cause of morbidity and mortality. While genetic variants have
been found to influence the risk of type 2 diabetes mellitus, relatively few studies have …

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes

MG Pezzolesi, GD Poznik, JC Mychaleckyj… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Despite extensive evidence for genetic susceptibility to diabetic nephropathy,
the identification of susceptibility genes and their variants has had limited success. To …

Genetics of diabetes mellitus and diabetes complications

JB Cole, JC Florez - Nature reviews nephrology, 2020 - nature.com
Diabetes is one of the fastest growing diseases worldwide, projected to affect 693 million
adults by 2045. Devastating macrovascular complications (cardiovascular disease) and …

[HTML][HTML] GWAS of diabetic nephropathy: is the GENIE out of the bottle?

CA Böger, JR Sedor - 2012 - journals.plos.org
Diabetic nephropathy (DN) is associated with excess morbidity and mortality, in both type 1
(T1D) and type 2 (T2D) diabetic patients. Despite intensification of treatment, DN remains a …

High-density single nucleotide polymorphism genome-wide linkage scan for susceptibility genes for diabetic nephropathy in type 1 diabetes: discordant sibpair …

JJ Rogus, GD Poznik, MG Pezzolesi, AM Smiles… - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Epidemiological and family studies have demonstrated that susceptibility
genes play an important role in the etiology of diabetic nephropathy, defined as persistent …

Genetics of diabetic microvascular disease

N Sandholm, C Forsblom - Microvascular Disease in Diabetes, 2020 - Wiley Online Library
Diabetic microvascular complications, affecting the kidneys, retina, and the nervous system,
are a heavy burden for both the diabetic individual and society. The complications seem to …

European rational approach for the genetics of diabetic complications—EURAGEDIC: patient populations and strategy

L Tarnow, PH Groop, S Hadjadj… - Nephrology Dialysis …, 2008 - academic.oup.com
Background. Diabetic nephropathy is likely to be a complex genetic trait. To date, most
diabetic nephropathy candidate gene studies have tested a limited number of genes and …